systemic antibiotics and locally applied antimicrobial agents have been suggested to enhance clinical parameters. patients exhibiting aggressive periodontitis in particular benefit from adjunctive antibiotic therapy. the purpose of this investigation was to evaluate the effect of local antibiotic therapy with metronidazole adjunctively to scaling and root planning (srp) in the treatment of aggr...

systemic antibiotics in conjunction with scaling and root planing (srp), can offer an additional benefi t over srp alone in the treatment of periodontitis, in terms of clinical attachment loss (cal) and pocket depth change, and reduced risk of additional cal loss. however, antibiotics are not innocuous drugs. their use should be justifi ed on the basis of a clearly established need and should n...

The local delivery of antibiotics in the treatment of osteomyelitis has been used safely and effectively for decades. Multiple methods of drug delivery have been developed for the purposes of both infection treatment and prophylaxis. The mainstay of treatment in this application over the past 20 years has been non-biodegradable polymethylmethacrylate, which has the advantages of excellent eluti...

UNLABELLED Infectious complications and their consequences are still key issues in rectal cancer surgery. Currently, intravenous antibiotic administration is a recognized method for lowering the rate of these complications. The aim of the study was to assess the efficacy of complementary application of a gentamicin-impregnated sponge in the perineal wound or in the vicinity of intestinal anasto...

the aim of this study was to determine the incidence and causes of fever as a major problem contributing to transplantation related mortality among patients undergoing hematopoietic stem cell transplantation (hsct) and evaluation of antibiotic use, according to reliable guidelines.we retrospectively reviewed hospital records of 195 adult patients who underwent hsct between 2009-2011 at hematolo...

Executive Summary Introduction Methodology Used to Prepare the Guideline Epidemiology Incidence Etiology Major Epidemiologic Points Pathogenesis Major Points for Pathogenesis Modifiable Risk Factors Intubation and Mechanical Ventilation Aspiration, Body Position, and Enteral Feeding Modulation of Colonization: Oral Antiseptics and Antibiotics Stress Bleeding Prophylaxis, Transfusion, and Glucos...