non-alcoholic steatohepatitis (nash) is a disease of unknown origin characterized histologically by alcoholic-like liver injury in the absence in the absence of significant alcohol intake. this study was conducted to assess the clinical and pathological features of nash patients in iran. patients with elevated liver transaminases, negative serologic markers of viral or autoimmune hepatitis and ...

background: regarding to the growing prevalence of nonalcoholic fatty liver disease (nafld), concentrating on various strategies to its prevention and management seems necessary. the aim of this study was to determine the effects of symbiotic on c‑reactive protein (crp), liver enzymes, and ultrasound findings in patients with nafld. methods: eighty nafld patients were enrolled in this randomize...

background: accumulation of triglycerides in the liver i.e. steatosis, is a well-known side-effect of tamoxifen administration to patients suffering from breast cancer. cichoriumintybus (chicory) is a plant used as traditional medicine for curing liver disorders. in this study, the effects of extract prepared from chicory roots on tamoxifen-induced liver steatosis and related biochemical factor...

background hbv infection is a serious public health problem worldwide, which can contribute to the incidence of chronic hepatitis b (chb), cirrhosis, and hepatocellular carcinoma (hcc). objectives in the present report, we assessed the association between adiponectin, its receptors and hepatic steatosis, fibrosis, and inflammation with hepatitis b virus. patients and methods liver biopsies from...

Background: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease (CLD). Omega-3 fatty acids and antioxidants co-supplementation have been considered as an alternative treatment in NAFLD. This trial will evaluate camelina sativa oil (CSO) effects as a rich source of omega-3 fatty acids and antioxidants on cardiometabolic risk factors, metabolic endotoxemia, liver en...

Background: Hepatic steatosis is commonly observed in patients with chronic hepatitis C (CHC). Many studies indicate a relationship between steatosis and fibrosis progression. The aim of this study was to analyze the prevalence of hepatic steatosis and related factors in Iranian CHC patients.   Methods: One hundred and fifteen consecutive patients with CHC were enrolled which were treat...

background: recent studies demonstrated that resveratrol has many therapeutic effects on liver disorders. resveratrol significantly increased survival after liver transplantation, decreased fat deposition, necrosis, and apoptosis which induced by ischemia in wistar rats. it provided liver protection against chemical, cholestatic, and alcohol injury. resveratrol can improve glucose metabolism an...

conclusions fap is an accurate, reliable, and noninvasive approach that can also be combined with other metabolic biomarkers to comprehensively detect and quantify hepatic steatosis. results the difference in fap was significant (p < 0.001) between chb-only patients and chb patients with hepatic steatosis. the cytokeratin 18 fragment (ck18-m65) level was significantly higher in chb patients wit...

Non-alcoholic fatty liver disease (NAFLD) is emerging as a major health problem worldwide. NAFLD is a continuum of disease ranging from mild liver steatosis to severe steatohepatitis, which will ultimately lead to end-stage liver disease with high morbidity and mortality rates. This disorder is considered as a silent liver disease. The metabolic syndrome and its components are accounted as the ...