background: including multivariate survival data can be pointed competing risks data. there are various methods to analyze such data such as semi-parametric methods of cause-specific hazard function, and cumulative incidence function. the aim of this study was to deploy competing risks model to analyze the determinants of patients with liver cirrhosis. materials and methods: during the one-year...

background: occupational lead poisoning is common in workers of some industries, but lead hepatotoxicity has rarely been reported. several animal studies have revealed lead induced liver damage but clinical studies concerning the manifestations of lead induced liver toxicity in humans are scares. this study was designed to investigate the clinical manifestations and pathological parameters of h...

recognition of typhoid hepatitis is important since it has to be differentiated from other common ailments in our country such as viral, malarial or amoebic hepatitis. early institution of specific therapy in cases of typhoid hepatitis carries a good prognosis. in our study, 107 patients with positive blood or bone marrow cultures for salmonella typhi, were evaluated for hepatomegaly and abnorm...

conclusions any discrepancy between histopathologic changes in time-zero biopsies and pattern of early liver laboratory alterations may be considered as a warning for causes other than pri. objectives the aim of this study was to show the correlation between histopathologic changes of pri and the alterations in liver tests in the early post-transplantation period. materials and methods between ...

background:methotrexate (mtx) is one of the most commonly used disease-modifying antirheumatic drugs in the treatment of rheumatoid arthritis (ra) which can be associated with toxic effects on different organs. this study was designed to investigate the hepatotoxic effects in ra patients treated with mtx. methods: in this cross-sectional observational study, ra patients who received standard do...

gabapentin (gpn) is a new antiepileptic agent currently in used as add-on therapy in adult patients suffering from partial seizures. the extent of liver damage at different dosage and long term treatment with gpn is not yet clear. therefore this study was undertaken to find out the possibility of liver damage by this drug. adult male (wistar) rats of 180-220 g were administered intraperitoneall...

background: thalassemia is one of the most common hereditary disorders and beta-thalassemia major is its severe form. the present study is concerned with the analysis of liver function, thyroid function and estimation of critical serum ions as well as hematological characteristics in beta-thalassemia patients and controls. subjects and methods: the study included 54 patients with beta-thalassem...

the effects of dietary nucleotide (nt) were evaluated on some serum biochemical parameters and acute stress responses of the catfish (pangasianodon hypophthalmus). five experimental diets including 0, 0.25, 0.5, 0.75, and 1% nt were supplied to catfish fry for 10 weeks. at the end of the experiment, fish fed the control and 1% nt diets were subjected to handling and crowding stress. the results...

teucrium polium is an analgesic, antidiabetic and antilipeidemic herbal medicament. the aim of this survey was to evaluate the effect of aqueous extract t. polium on liver enzymes linked to liver dysfunction, serum lipids and glucose, in diabetic male rats. methods: a total of 20 sprague-dawly male rats became diabetic by intraperitoneal injection of streptozotocin (60 mg/kg). the animals were ...