BACKGROUND Vernonia amygdalina, commonly called bitter-leaf, is widely consumed in many parts of Africa, and Nigeria, in particular. The leaf extract has been reported to have antimicrobial, anti-plasmodial, anti-helminthic, as well as prebiotic properties, but its immuno-modulatory effects have not been well-studied, neither have the prebiotics been identified. This study evaluated the immuno-...

Effect of Dietary Supplementation Liquid Prebiotic and Antibiotic on Egg Production, Quality, Blood Parameters, Immune System Response Layer Hens at Post Molt Period

Following his seminal work in 1953, Stanley Miller conducted an experiment in 1958 to study the polymerization of amino acids under simulated early Earth conditions. In the experiment, Miller sparked a gas mixture of CH4, NH3, and H2O, while intermittently adding the plausible prebiotic condensing reagent cyanamide. For unknown reasons, an analysis of the samples was not reported. We analyzed t...

A prebiotic is "a selectively fermented ingredient that allows specific changes, both in the composition and/or activity in the gastrointestinal microflora that confers benefits upon host well-being and health." Today, only 2 dietary nondigestible oligosaccharides fulfill all the criteria for prebiotic classification. The daily dose of the prebiotic is not a determinant of the prebiotic effect,...

The origin of life is still an unsolved mystery in science. Hypothetically, prebiotic chemistry and the formation of protocells may have evolved in the hydrothermal environment of tectonic fault zones in the upper continental crust, an environment where sensitive molecules are protected against degradation induced e.g. by UV radiation. The composition of fluid inclusions in minerals such as qua...

Fermentation properties of oligosaccharides derived from orange peel pectin were assessed in mixed fecal bacterial culture. The orange peel oligosaccharide fraction contained glucose in addition to rhamnogalacturonan and xylogalacturonan pectic oligosaccharides. Twenty-four-hour, temperature- and pH-controlled, stirred anaerobic fecal batch cultures were used to determine the effects that oligo...

Largest satellite of Saturn and the only in the solar system having a dense atmosphere, Titan is one of the key planetary bodies for astrobiological studies, due to several aspects. (i) Its analogies with planet Earth, in spite of much lower temperatures, with, in particular, a methane cycle on Titan analogous to the water cycle on Earth. (ii) The presence of an active organic chemistry, involv...

An experiment has been conducted to evaluate the effects of a liquid prebiotic (LP) on the carcass, digestive tract, and productive traits of Japanese quail. Eighty 7-day-old Japanese quails were randomly divided into 2 treatments. Each treatment consisted of 4 replicates (pens) of 10 birds each. The first treatment (control) contained a standard recommended diet with no added prebiotic. The se...