نتایج جستجو برای: liposome dha epa

تعداد نتایج: 18144  

Journal: :iranian journal of pharmaceutical research 0
zahra hadian shaheed beheshti university of medical sciences mohammad ali sahari tarbiat modares university hamid reza moghimi department of pharmaceutics, faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran. mohsen barzegar department of food science and technology, faculty of agriculture, tarbiat modares university, tehran, iran.

omega-3 fatty acids (fas) have been shown to prevent cardiovascular disease. the most commonly used omega-3 fatty acids like eicosapentaenoic acid (epa) and docosahexaenoic acid (dha) are highly vulnerable to oxidation and therefore, have short shelf life. recent advances in nanoliposomes provided a biocompatible system for stabilizing omega-3 fas. several methods could be implemented to prepar...

Omega-3 fatty acids (FAs) have been shown to prevent cardiovascular disease. The most commonly used omega-3 fatty acids like eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are highly vulnerable to oxidation and therefore, have short shelf life. Recent advances in nanoliposomes provided a biocompatible system for stabilizing omega-3 FAs. Several methods could be implemented to prepar...

Omega-3 fatty acids (FAs) have been shown to prevent cardiovascular disease. The most commonly used omega-3 fatty acids like eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are highly vulnerable to oxidation and therefore, have short shelf life. Recent advances in nanoliposomes provided a biocompatible system for stabilizing omega-3 FAs. Several methods could be implemented to prepar...

Journal: :The Journal of pharmacology and experimental therapeutics 2010
Ramzi J Khairallah Karen M O'Shea Bethany H Brown Nishanth Khanna Christine Des Rosiers William C Stanley

Intake of fish oil containing docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) prevents heart failure; however, the mechanisms are unclear. Mitochondrial permeability transition pore (MPTP) opening contributes to myocardial pathology in cardiac hypertrophy and heart failure, and treatment with DHA + EPA delays MPTP opening. Here, we assessed: 1) whether supplementation with both DHA a...

2010
Ramzi J. Khairallah Karen M. O’Shea Bethany H. Brown Nishanth Khanna Christine Des Rosiers William C. Stanley

Intake of fish oil containing docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) prevents heart failure; however, the mechanisms are unclear. Mitochondrial permeability transition pore (MPTP) opening contributes to myocardial pathology in cardiac hypertrophy and heart failure, and treatment with DHA EPA delays MPTP opening. Here, we assessed: 1) whether supplementation with both DHA and...

2018
Jacqueline K. Innes Philip C. Calder

A large body of evidence supports the cardioprotective effects of the long-chain omega-3 polyunsaturated fatty acids (PUFAs), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). There is increasing interest in the independent effects of EPA and DHA in the modulation of cardiometabolic risk factors. This systematic review aims to appraise the latest available evidence of the differentia...

Journal: :Prostaglandins, leukotrienes, and essential fatty acids 2011
Martine F Luxwolda Remko S Kuipers Ella N Smit Francien V Velzing-Aarts D A Janneke Dijck-Brouwer Frits A J Muskiet

INTRODUCTION The relation between docosahexaenoic (DHA) and eicosapentaenoic (EPA) vs. arachidonic acid (AA) seems characterized by both synergism and antagonism. MATERIALS AND METHODS Investigate the relation between EPA+DHA and AA in populations with a wide range of EPA+DHA status and across the life cycle. EPA+DHA and AA were determined in erythrocytes (RBC; n=1979), umbilical arteries (UA...

2017
Adam H. Metherel Raphaël Chouinard-Watkins Marc-Olivier Trépanier R. J. Scott Lacombe Richard P. Bazinet

Dietary docosahexaenoic acid (DHA, 22:6n-3) not only increases blood and tissue levels of DHA, but also eicosapentaenoic acid (EPA, 20:5n-3). It is generally believed that this increase is due to DHA retroconversion to EPA, however, a slower conversion of α-linolenic acid (ALA, 18:3n-3) derived EPA to downstream metabolic products (i.e. slower turnover of EPA) is equally plausible. In this stud...

Journal: :Public health nutrition 2009
Michel Lucas Geneviève Asselin Chantal Mérette Marie-Josée Poulin Sylvie Dodin

OBJECTIVE To validate an FFQ for the assessment of dietary EPA and DHA against their relative concentrations in red blood cells (RBC). DESIGN Cross-sectional analysis of baseline data. Intakes of marine food products and EPA and DHA were estimated by FFQ on the basis of consumption of marine food products in the last month. Fatty acid composition of RBC membranes was quantified by GC. SETTI...

Journal: :American journal of physiology. Cell physiology 2013
Mark K Larson Garth W Tormoen Lucinda J Weaver Kristen J Luepke Ishan A Patel Carl E Hjelmen Nicole M Ensz Leah S McComas Owen J T McCarty

Several studies have implicated the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in inhibition of normal platelet function, suggesting a role for platelets in EPA- and DHA-mediated cardioprotection. However, it is unclear whether the cardioprotective mechanisms arise from alterations to platelet-platelet, platelet-matrix, or platelet-coagulation factor interact...

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