Ammonium sulfate is one of the subsidiary components in the stealth liposome structure. The ratio of ammonium ion bound to liposome sphere to ammonium ions outside the liposome plays an important role in drug delivery formulation; accordingly, in order to quantify the ammonium ion in the liposome structure, a rapid and sensitive method was validated using a conductivity detector. Through this m...

Erlotinib (ELT) as a small molecule with poor solubility, poor bioavailability, and instability in gastrointestinal environment, has been considered as a therapeutic agent for Non-Small-Cell Lung Cancer (NSCLC) therapy through oral administration. In the present study, ELT-liposome and ELT-NLCs were successfully prepared and characterized by assessment of the particle size, zeta potential (ZP),...

the use of liposome as an adjuvant and a vaccine carrier has been cited previously in the literature. it has also been shown to be effective in enhancing the immunogenicity of vaccine candidates. balb/c mice immunized subcutaneously with outer membrane protein (omp) of brucella abortus s19 vaccine strain entrapped in a commercial cationic liposome (s19-omp-liposome) for vaccine delivery, showed...

Abstract Background Cosmeceuticals are cosmetic products with biologically active components that have drug-like benefits. currently rapidly growing segments encompassing the personal care industry and numerous topical cosmetics-based therapies for treating different skin conditions. The barrier nature of causes limitations to treatment. effectiveness this cosmeceutical product has been enhance...

Humans are the most crucial host of Salmonella Typhi as it has limited ability to reproduce outside human body. infections caused Typhoid fever which can be prevented with vaccines. This study aims develop an effective typhoid oral vaccine using a liposomal delivery system. Several studies showed that immunization AdhO36 protein from orally provides significant protection in inhibiting mice int...

The use of liposome as an adjuvant and a vaccine carrier has been cited previously in the literature. It has also been shown to be effective in enhancing the immunogenicity of vaccine candidates. BALB/c mice immunized subcutaneously with outer membrane protein (OMP) of Brucella abortus S19 vaccine strain entrapped in a commercial cationic liposome (S19-OMP-liposome) for vaccine delivery, showed...

Erlotinib (ELT) as a small molecule with poor solubility, poor bioavailability, and instability in gastrointestinal environment, has been considered as a therapeutic agent for Non-Small-Cell Lung Cancer (NSCLC) therapy through oral administration. In the present study, ELT-liposome and ELT-NLCs were successfully prepared and characterized by assessment of the particle size, zeta potential (ZP),...

objective(s): soluble leishmania antigens (sla) provide suitable protection against leishmaniasis in murine model when delivered by an appropriate delivery system. liposomes have been shown to be suitable vaccine delivery systems against leishmaniasis, however, the phospholipase-a (pla) activity of sla is a drawback to prepare a stable liposomal sla. one strategy to overcome this problem might ...

Incorporation of membrane proteins into reconstituted lipid membranes is a common approach for studying their structure and function relationship in native-like environment. In this work, we investigated fluorescence properties liposome-reconstituted major light-harvesting complexes plants (LHCII). By utilizing liposome labelling with the fluorescent dye molecules single-molecule microscopy tec...