نتایج جستجو برای: lipooligosaccharide

تعداد نتایج: 563  

Journal: :Infection and immunity 2002
Shuhua Sun N Karoline Scheffler Bradford W Gibson Jing Wang Robert S Munson

Haemophilus ducreyi is the causative agent of chancroid, a sexually transmitted ulcerative disease. In the present study, the Neisseria gonorrhoeae lgtA lipooligosaccharide glycosyltransferase gene was used to identify a homologue in the genome of H. ducreyi. The putative H. ducreyi glycosyltransferase gene (designated lgtA) was cloned and insertionally inactivated, and an isogenic mutant was c...

Journal: :Infection and immunity 1988
Z M Li J L Cowell M J Brennan D L Burns C R Manclark

Monoclonal antibodies that specifically agglutinate strains of Bordetella pertussis having serotype 1 agglutinogen were uniquely reactive with the electrophoretically slow-migrating A form of lipooligosaccharide. These monoclonal antibodies should be useful for the structural analysis of B. pertussis lipooligosaccharide and for the establishment of a better-defined serogroup for Bordetella spec...

1998
Michael D. Howard Thomas J. Inzana Mitzi Nagarkatti

Antigenic Characterization of Haemophilus somnus Lipooligosaccharide

Journal: :Infection and immunity 2009
Lisa A Lewis Biswa Choudhury Jacqueline T Balthazar Larry E Martin Sanjay Ram Peter A Rice David S Stephens Russell Carlson William M Shafer

The capacity of Neisseria gonorrhoeae to cause disseminated gonococcal infection requires that such strains resist the bactericidal action of normal human serum. The bactericidal action of normal human serum against N. gonorrhoeae is mediated by the classical complement pathway through an antibody-dependent mechanism. The mechanism(s) by which certain strains of gonococci resist normal human se...

Journal: :Infection and immunity 1995
R K Pettit E S Martin S M Wagner V J Bertolino

Neisseria gonorrhoeae infects a diverse array of niches in its human host, which expose the organism to dramatic variations in pH. We examined growth and lipooligosaccharide expression of two gonococcal strains in liquid and solid cultures under acidic, neutral, and alkaline conditions. Growth rates in broth were similar under the three conditions, and the pH remained fairly constant throughout...

Journal: :Infection and immunity 2014
Carmen Puig Sara Marti Peter W M Hermans Marien I de Jonge Carmen Ardanuy Josefina Liñares Jeroen D Langereis

Nontypeable Haemophilus influenzae (NTHi) is an opportunistic pathogen that causes otitis media in children and community-acquired pneumonia or exacerbations of chronic obstructive pulmonary disease in adults. A large variety of studies suggest that biofilm formation by NTHi may be an important step in the pathogenesis of this bacterium. The objective of this report was to determine the relatio...

Journal: :Infection and immunity 1987
R C Judd M Tam K Joiner

The protein IAs of serum-sensitive (FA635) and serum-resistant (FA638) transformants of Neisseria gonorrhoeae, which have identical pedigrees, have been shown to be different by the use of a monoclonal antibody and were also shown to be different by proteinase K cleavage and primary structural and surface peptide mapping. The difference in structure is within the surface-exposed region of the m...

Journal: :vaccine research 0
amin arsang department of microbiology, pasteur institute of iran, tehran, iran, department of mycobacteriology & pulmonary research, pasteur institute of iran, tehran, iran shamsi yari department of mycobacteriology & pulmonary research, pasteur institute of iran, tehran, iran morteza masoumi department of mycobacteriology & pulmonary research, pasteur institute of iran, tehran, iran ali nour neamatollahi department of mycobacteriology & pulmonary research, pasteur institute of iran, tehran, iran farzam vaziri department of mycobacteriology & pulmonary research, pasteur institute of iran, tehran, iran mehdi nejati department of bacterial vaccine, pasteur institute of iran, tehran, iran

introduction : haemophilus influenzae type b (hib) is a gram negative bacterium and one of the causative agents of acute bacterial meningitis, especially in infants and children less than 5 years old. lipooligosaccharide (los), one of the virulence factors which plays an important role in pathogenesis of hib, has multiple applications in diagnosis and conjugate vaccines. in this study, los extr...

Journal: :Journal of Biological Chemistry 2011

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
Nobuhiro Yuki Keiichiro Susuki Michiaki Koga Yukihiro Nishimoto Masaaki Odaka Koichi Hirata Kyoji Taguchi Tadashi Miyatake Koichi Furukawa Tetsuji Kobata Mitsunori Yamada

Molecular mimicry between microbial and self-components is postulated as the mechanism that accounts for the antigen and tissue specificity of immune responses in postinfectious autoimmune diseases. Little direct evidence exists, and research in this area has focused principally on T cell-mediated, antipeptide responses, rather than on humoral responses to carbohydrate structures. Guillain-Barr...

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