BACKGROUND Lipofilling is widely used in breast reconstruction after mastectomy with reconstruction or breast conserving surgery in patients with breast cancer. The aim of this study is focused on complications associated with lipofilling in elderly breast cancer patients with breast defects after breast conserving surgery or reconstruction. METHODS A total of 137 patients older than 60 years...

The following case series describes the treatment of neuropathic pain in post-surgical scars, using adipocytes and adipose-derived stem/progenitor cells (ASCs). Two cases are described in which patients underwent lipofilling to treat painful scars after cosmetic surgery. The primary indication for lipofilling was pain reduction and not improved cosmesis. Numeric rating scale (NRS) values were r...

Milan, Italy; Paris and Lyon, France; and Bangkok, Thailand Background: Lipofilling is now performed to improve the breast contour, after both breast-conserving surgery and breast reconstruction. However, injection of fat into a previous tumor site may create a new environment for cancer and adjacent cells. There is also no international agreement regarding lipofilling after breast cancer treat...

BACKGROUND Lipofilling is now performed to improve the breast contour, after both breast-conserving surgery and breast reconstruction. However, injection of fat into a previous tumor site may create a new environment for cancer and adjacent cells. There is also no international agreement regarding lipofilling after breast cancer treatment. METHODS The authors included three institutions speci...

BACKGROUND Lipofilling has been indicated for postmastectomy and postlumpectomy breast reconstruction. The clinical literatures underline its technical efficacy but experimental studies raise important questions about the potential detrimental effect of adipocytes on the stimulation of cancer growth and reappearance. DESIGN We collected 321 consecutive patients operated for a primary breast c...

Introduction: Lipofilling is a useful surgical technique for breast reconstruction. However, there remains a concern regarding the long-term safety of fat grafting with its stem cell population in breast cancer patients. This study evaluated the safety of lipofilling procedure in breast reconstruction. Materials and Methods: We conducted this observational study that included patients who under...

www.PRSJournal.com 385 A survey of the American Society of Plastic Surgeons in 2010 regarding the safety of autologous fat grafting (lipofilling) of the breast found that 49 percent of respondents considered the lack of evidence supporting the oncologic safety of lipofilling to be a significant obstacle to its use for breast reconstruction or cosmetic augmentation.1 A concern is that adult adip...

BACKGROUND Fat grafting is widely carried out in breast cancer patients to improve quality in breast reconstruction. Recently, in vitro and animal studies have questioned the role of adipose tissues in cancer development. DESIGNS Matched-cohort study. We analysed: (i) 59 intraepithelial neoplasia patients who had undergone lipofilling, with no recurrence between primary surgery and lipofillin...

L ipofilling is the removal of fat by liposuction, which is then injected into the desired region of the body for volume enhancement. However, the technique is not new and more than 125 years ago the alleged potential of living fat cells as fillers was explored. Lipofilling has regained popularity in recent decades. Prior to 1966 there was criticism of the scientific knowledge and personal expe...

BACKGROUND Although many plastic surgeons perform autologous fat grafting (lipofilling) for breast reconstruction after oncologic surgery, it has not been established whether postoncologic lipofilling increases the risk of breast cancer recurrence. The authors assessed the risk of locoregional and systemic recurrence in patients who underwent lipofilling for breast reconstruction. METHODS The...