generalized lipodystrophy is a rare disorder in children characterized by absence of subcutaneous adipose tissue. we evaluated 10 patients with generalized lipodystrophy by skin and liver biopsy. eight patients with steatohepatitis and cirrhosis were treated with ursobile (uorsodeoxycholic acid) and vitamin e. in follow-up, serum triglyceride level was decreased.

BACKGROUND HIV disease itself is associated with increased healthcare utilization and healthcare expenditures. HIV-infected persons with lipodystrophy have been shown to have poor self-perceptions of health. We evaluated whether lipodystrophy in the HIV-infected population was associated with increased utilization of healthcare services and increased healthcare costs. OBJECTIVE To examine uti...

Context Lipodystrophy syndromes are characterized by generalized or partial absence of adipose tissue. Objective We conducted a systematic review to synthesize data on clinical and metabolic features of lipodystrophy (age at onset, < 18 years). Data Source Sources included Medline, Embase, Cochrane Library, Scopus and Non-Indexed Citations from inception through January 2016. Study Select...

BACKGROUND Lipodystrophy and dyslipidemia are increasing problems in HIV-infected patients receiving antiretroviral therapy (ART). OBJECTIVE Determine the prevalence and predicting factors for lipodystrophy and dyslipidemia in these patients. MATERIAL AND METHOD A cross-sectional study was performed on HIV-infected patients receiving ART in January 2006. Clinical assessment for lipodystroph...

Introduction: Lipodystrophy is related to the use of highly active antiretroviral therapy (HAART) and can cause aesthetic stigma and increase the risk of developing cardiovascular diseases. Physical activity may be a valid alternative for the treatment and prevention of lipodystrophy. However, few studies address this issue. The objective of this study was to assess lipodystrophy related to hig...

BACKGROUND Lipodystrophy is a known adverse effect of highly active antiretroviral therapy (HAART). Lipodystrophy resulting in body dysmorphism can lower the quality of life (QoL) among HAART recipients. The main aim of our study was to find the effect of lipodystrophy on QoL among people living with HIV (PLHIV) on HAART. METHODS This cross-sectional study was conducted in a tertiary care hos...

BACKGROUND HIV lipodystrophy syndrome is a recognized complication of potent antiretroviral therapy and is characterized by often dramatic changes in various body fat stores, both central and peripheral. Given prior findings of heightened body image dysphoria among HIV-infected men with lipodystrophy as compared to HIV-infected men without lipodystrophy, we sought to determine body image among ...

Background HIV infection and long-term HAART use are associated with metabolic and morphological changes. We assessed prevalence, types, and risk factors associated with lipodystrophy among HIV-infected adults attending CTC in Dar es Salaam, Tanzania. Methods Analysis included 466 HIV-infected patients. Study protocol involved administration of structured questionnaire to collect sociodemogra...

Dermatomyositis is an idiopathic inflammatory myopathy, with skin manifestations. A less frequently recognized but clinically important complication of dermatomyositis is lipodystrophy (LD), and associated metabolic abnormalities that increasingly recognized as complications of juvenile dermatomyositis. Lipodystrophy is less frequently reported in adult onset dermatomyositis.In this paper we ar...