free radicals involved in a number of diseases due to the oxidative damage to dna, lipids, and proteins and which can result in failure of cellular functions. dried plant bulbs and leaves methanolic and ethanolic extracts were prepared. total antioxidant activities of the methanolic extracts of romulea ramiflora and gagea fibrosa were determined using β-caroten-linoleic acid assay. romulea-bulb...

Background: For understanding the roles of fatty acids on the induction of acrosome reaction which occurs under association of cholesterol efflux and PKA or PKC pathways in boar spermatozoa, metabolic fate of alone and combined radiolabeled 14C-oleic acid and 3H-linoleic acid incorporated in the sperm was compared, and behavior of cholesterol and effects of PKA and PKC inhibitors upon fatty aci...

The essential oil (EO) obtained by hydrodistillation from Teucrium polium L. was analyzed by gas chromatography and gas chromatography mass spectrometry (GC/MS). Antioxidant activity was evaluated through DPPH assay and Beta-carotene/linoleic acid assay. Twenty one components were identified representing (90.4%) of the EO. Main constituents of the essential oil were found as Spathulenol (15.06%...

The genus Verbascum L. belongs to the family Scrophulariaceae and includes plants that have been used widely in traditional medicine for a long time. Methanolic extracts of three Verbascum species from flora of Iran were in vitro screened for their possible antioxidant activities by three complementary test systems, namely DPPH free radical-scavenging, metal chelating activity and β-carotene/li...

background: breast cancer is one of the main life-threatening diseases which a woman may face during her life. several lifestyle factors such as weight gain, obesity, fat intake and decreased level of physical activity are associated with breast cancer risk.   in vitro and vivo studies showed that, linoleic acid (la) is one of the main fatty acids composition of nigella sativa. the objective wa...

This paper focused on the assessment of antioxidant property and fatty acid composition of four Centaurea species. The antioxidant activity of its methanol extract was evaluated by several in vitro experiments including phosphomolybedum assay, DPPH assay, β-carotene/linoleic acid, ferric and cupric reducing power. Total phenolic and flavonoid contents were also evaluated. The methanol extract o...

OBJECTIVE Polyunsaturated fatty acids such as linoleic acid are well known dietary lipids that may be atherogenic by activating vascular endothelial cells. In the liver, fatty acids can be metabolized by cytochrome P450 (CYP) enzymes, but little is known about the role of these enzymes in the vascular endothelium. CYP 2C9 is involved in linoleic acid epoxygenation, and the major product of this...

the genus verbascum l. belongs to the family scrophulariaceae and includes plants that have been used widely in traditional medicine for a long time. methanolic extracts of three verbascum species from flora of iran were in vitro screened for their possible antioxidant activities by three complementary test systems, namely dpph free radical-scavenging, metal chelating activity and β-carotene/li...

Skin diseases can get natural therapies from medicinal plant-based products. In this study, a topical cream was formulated ethanol extract of Acacia sieberiana, beeswax and Vitellaria paradoxa (shea) butter. GC-MS characterization with co-injection the revealed Stearic acid (31.43%), Palmitic (23.15%), Oleic (21.44%) Linoleic (16.20%) as major components. Seven phenolic conpounds were identifie...

BACKGROUND Linoleic acid is the most abundant polyunsaturated fatty acid in human nutrition and found in most vegetable oils and certain food products. In the present study, we investigated the effects of linoleic acid on the growth of human epithelial adenocarcinoma AGS cells. METHODS MTT assay, flow cytometry, RT-PCR and Western-blot analyses were used to investigate the effects and underly...