lps-responsive beige-like anchor (lrba) deficiency is a disease which has recently been described in a group of patients with common variable immunodeficiency (cvid) in association with autoimmunity and/or inflammatory bowel disease (ibd)-like phenotype. we here describe a 10-year-old boy who experienced recurrent infections, mainly in the respiratory system, associated with thrombocytopenia an...

Abstract Building on the work of Fyodorov (2004) and Nadal (2012) we examine critical behaviour population saddles with fixed instability index k in high dimensional random energy landscapes. Such landscapes consist a parabolic confining potential part N ? 1 dimensions. When relative strength m is decreasing below value c , exhibit glass-like transition from simple phase very few points to comp...

Figure: Averaged normalized importances for X1 from 100 simulated datasets (simulation process described below) for m=1,2,3,4 (left to right) with β1=(4,1,1,0.3) , corr(Xj,Xk)=ρ |j−k| with ρ=−0.9 to 0.9 in steps of 0.1 Grey line: true normalized LMG allocation; Black line: true normalized PMVD allocation : Variable importance (% MSE Reduction) from RF-CART; ×: Variable importance (% MSE Reducti...

the technique described below offers temporary crown for the severely damaged vital anterior teeth without resorting to emergency root canal therapy or pin.