objective: to compare the efficacy of emla cream and lidocaine injection to reduce pain during episiotomy repair. materials and methods: a total of 46 primiparous women with normal pregnancy who referred for normal vaginal delivery and needed episiotomy repair were selected and randomly divided into two groups. for emla group, one hour before the estimated time of delivery, 5g of emla cream was...

Local anesthetic creams for the clinical treatment of conditions such as postherpetic neuralgia were prepared as an in-house formulation from the eutectic mixture of lidocaine-tetracaine (LT cream) using two eutectic mixtures of local anesthetic (EMLA) type bases. The LT formulation was compared with a lidocaine-prilocaine (LP cream) eutectic mixture formulated using the same base as EMLA. The ...

Urethral catheterization is a predictor of agitation during the general anesthesia recovery period. The aim of this study was to determine the effect of intraurethral 5% lidocaine and 25 mg/g prilocaine cream in reducing catheter-related bladder discomfort (CRBD) in male patients during the general anesthesia recovery period. Adult male patients undergoing elective operations that required urin...

The lidocaine-prilocaine cream (EMLATM) effectively reduces the pain from debridement of chronic leg ulcers. Studies have demonstrated that when applied to leg ulcers, plasma concentrations of the local anaesthetics are well below the threshold for CNS toxicity. However, there are minimal pharmacokinetic data available from EMLA application to burn wounds. This study evaluated EMLA cream for de...

PURPOSE To investigate the efficacy of a novel anesthetic technique called iliohypogastric nerve block (INB) for pain control in patients undergoing prostate biopsy. MATERIALS AND METHODS A total of 59 consecutive patients who underwent transrectal ultrasound guided prostates biopsies were included in the study. Patients were randomized into four groups: (1) control, no method of anesthesia w...

The author of the above-mentioned paper would like to make the following adjustment to her article. In the last paragraph of the ‘Current Treatments’ section, the sentence currently reads ‘Lidocaine/tetracaine cream (Pliaglis , Galderma Laboratories, Texas, USA) is the first Food and Drug Administration (FDA)-approved stable compounded mixture of 7 % lidocaine and 7 % tetracaine cream.’ This se...

eutectic mixture of lidocaine and prilocaine (EMLA cream): comparison with placebo cream and no local premedication. Acta Anaesthesiol Scand 1987;31: 735-9. 8 Hallen B, Olsson GL, Uppfeldt A. Pain-free venepuncture. Effect of timing of application of local anaesthetic cream. Anaesthesia 1984;39:%9-72. 9 Hopkins CS, Buckley CJ, Bush GH. Pain-free injection in infants. Use of a lignocaine-priloca...

BACKGROUND Pain is a common adverse effect of dermatological laser procedures. Currently, no standard topical anaesthetic cream exists for deeper dermal laser procedures. OBJECTIVES To compare the efficacy of lidocaine/tetracaine cream and lidocaine/prilocaine cream in reducing self-reported pain during deeper dermal laser treatment of acne keloidalis nuchae (AKN) and tattoos. METHODS We co...

OBJECTIVE To determine whether pretreatment of skin with erbium:YAG (Er:YAG) laser-assisted delivery facilitates the penetration of lidocaine cream to provide anesthesia suitable for needlesticks after just 5 minutes. DESIGN Trial 1 was a double-blind randomized controlled trial, whereas trial 2 was a nonblinded randomized controlled trial. SETTING The study was conducted in 2 facilities, a...

BACKGROUND Acute neuropathic pain is a common disorder. Transdermal cream could be an alternative to oral medications. OBJECTIVE To evaluate the effectiveness and tolerability of transdermal Lidocaine and Ketamine for acute neuropathic pain. STUDY DESIGN Retrospective chart review SETTING University-affiliated outpatient Physiatry clinic METHODS ARTICIPANTS: neuropathic pain with a pres...