background: leydig cell tumor is a rare form of testicular neoplasm which comprises 1-3% of all testicular tumors and only about 3% of these tumors are bilateral. a few leydig all tumor have been described in patients with klinefelter�s syndrome so far. case: the patient described in this case report was a 24 year-old man with chief complaint of infertility for one year. physical examination, s...

leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. they produce testosterone leading to hyperandrogenism. we present a 41yr old woman with symptoms of virilization and a mass of right adenex via ultra sonography, and a rise of total and free serum testosterone. an ovarian source of androgen was suspected and a surgery performed. a diagnosis o...

leydig cell tumor as a sex-cord stromal tumor is a relatively uncommon ovarian tumorin bitch. a 10-year-old female german shepherd dog was presented because of protrusion of a large tumor-like mass of 16 × 14 × 7 cm in dimensions from her vagina. after stabilization of the patient, the mass was removed surgically and concurrent ovariohysterectomy was also performed. macroscopically, the healthy...

systemic amyloidosis and testicular interstitial tumor are rare conditions in birds and this is the first report in iran. a male zebra finch was presented because of white diarrhea, anorexia, loss of weight and lethargy. at necropsy, the small intestine was edematous and congested. the spleen appeared pale. the liver was large, firm and brown. one testis was cystic and neoplastic and the remain...

introduction: complete androgen insensitivity syndrome (previously called testicular feminization) is specified by a 46 xy karyotype and negative sex chromatin, bilateral undescended testes, female genitalia appearance, and lack of mullerian derivatives. discussion: our medline search revealed that this is the first reported case of bilateral sertoli–leydig cell tumor (slct) in androgen insensi...

 Leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. They produce testosterone leading to hyperandrogenism. We present a 41yr old woman with symptoms of virilization and a mass of right adenex via ultra Sonography, and a rise of total and free serum testosterone. An ovarian source of androgen was suspected and a surgery performed. A diagnosis ...

We Describe a case of ovarian serous cystadenoma having Sertoli-Leydig cell tumor, well differentiated, in the cystic septum. Well differentiated Sertoli-Leydig cell tumor coexisting with other tumor, including serous tumor, has not yet been described. In all cases of Sertoli-Leydig cell tumor with heterologous components or other tumors, the androblastomatous components are intermediately or p...

Leydig cell tumor as a sex-cord stromal tumor is a relatively uncommon ovarian tumorin bitch. A 10-year-old female German Shepherd dog was presented because of protrusion of a large tumor-like mass of 16 × 14 × 7 cm in dimensions from her vagina. After stabilization of the patient, the mass was removed surgically and concurrent ovariohysterectomy was also performed. Macroscopically, the healthy...

Leydig cell tumors are usually benign tumors of the male gonad. However, if the tumor is malignant, no effective treatments are currently available. Leydig cell tumors express platelet-derived growth factor (PDGF), kit ligand and their respective receptors, PDGFR and c-kit. We therefore evaluated the effects of imatinib mesylate (imatinib), a selective inhibitor of the c-kit and PDGFR tyrosine ...