BACKGROUND Oral squamous cell carcinoma (OSCC) is a challenging disease with a high mortality rate. Natural products represent a valuable source for the development of novel anticancer drugs. We investigated the cytotoxic potential of essential oil from the leaves of a medicinal plant, Levisticum officinale (lovage) on head and neck squamous carcinoma cells (HNSCC). MATERIALS AND METHODS Cyto...

Objective: According to previous publications, the erratic hereditary disease with the augmented urinary excretion of cystine, could be envisage as the key to major injury in complicated patients due to recurrent of kidney stones. Therefore, the aim of this study was to investigate the safety and efficacy of Levisticum officinale (Lovage) in patients with cystinuria Patients and methods: Patien...

Four important categories of urologic herbs, their history, and modern scientific investigations regarding them are reviewed. Botanical diuretics are discussed with a focus on Solidago spp (goldenrod) herb, Levisticum officinale (lovage) root, Petroselinum crispus (parsley) fruit, and Urtica dioica (stinging nettle) herb. Urinary antiseptic and anti-adhesion herbs, particularly Arctostaphylos u...

Background. Programs of preclinical safety studies the health care products depend on regulatory status investigated products. The classification such products, in particular suppositories for rectal and vaginal use, is a critical step developing tactics their biological evaluation. Adaptation evaluation methods medical devices based combination biologically active substances, as well results u...

acetylcholinesterase (ache) is the main enzyme for the breakdown of acetylcholine. nowadays, usage of the inhibitors of this enzyme is one of the most important types of treatment of mild to moderate neurodegenerative diseases such as alzheimer’s disease. herbal medicines can be a new source of inhibitors of this enzyme. in this study we examined around 100 different plants to evaluate their in...

DNA barcodes have been increasingly used in authentication of medicinal plants, while their wide application in materia medica is limited in their accuracy due to incomplete sampling of species and absence of identification for materia medica. In this study, 95 leaf accessions of 23 species (including one variety) and materia medica of three Pharmacopoeia-recorded species of Angelica in China w...

Background: The leaves, roots and seeds of Lovage (Levisticum officinale Koch) being used as an herb, vegetable and spice. Objective: The aim of this study is evaluation of the changes of phytochemical compound in aerial parts of the Lovage plants at different developmental stages as well as antioxidant activity. Methods: The plants were harvested from Hezar Mountain. After drying, essent...