background: given to the abundant incidence of malnutrition in hiv+ patients and its effect on progress of aids disease, several studies have recommended supplementation therapy (such as selenium, levamisole, zinc). methods: this clinical trial was prefunded on patient's with hiv + in behavior diseases consulting center, kermanshah, iran 2006-2007. one hundred-seventy eight out of all pati...

INTRODUCTION Numerous studies suggest that levamisole, an antihelmintic agent with an immunomodulatory effect, reduces the number of relapses in children with frequently relapsing and steroid-dependent nephrotic syndrome (FRNS/SDNS). The aim of the study was to present a single center's experience in treatment of FRNS and SDNS with levamisole. MATERIAL AND METHODS Among 72 children with FRNS/...

levamisole is an anthelmintic agent and also immunostimulant drug which is used to treat colorectal cancer. the present study aimed to show accidental consumption of levamisole alone induced multifocal inflammatory leukoencephalopathy. a 53-year-old male was admitted to the neurology department of farabi hospital (kermanshah, iran) with walking inability and recognition disorder. following clin...

Levamisole, a veterinary antihelminthic, was recently recognized as an adulterant in cocaine and is known to cause severe adverse reactions in some cocaine users. Because of the health concerns involving levamisole-adulterated cocaine, we developed a liquid chromatography-tandem mass spectrometry (LC-MS-MS) method for the detection of levamisole in urine. This method was used to determine the p...

Levamisole is an anthelmintic agent and also immunostimulant drug which is used to treat colorectal cancer. The present study aimed to show accidental consumption of levamisole alone induced multifocal inflammatory leukoencephalopathy. A 53-year-old male was admitted to the Neurology Department of Farabi Hospital (Kermanshah, Iran) with walking inability and recognition disorder. Following clin...

The therapeutic effect of a single weekly dose of levamisole in patients with rheumatoid arthritis was compared with placebo for 6 months in a 13-centre double-blind controlled study. 281 patients with classic or definite rheumatoid arthritis and active disease were evaluated. A single weekly dose of 150 mg levamisole was superior to placebo in controlling disease activity. A single weekly dose...

The Caenorhabditis elegans neuromuscular junction (NMJ) contains three pharmacologically distinct ionotropic receptors: gamma-aminobutyric acid receptors, levamisole-sensitive nicotinic receptors, and levamisole-insensitive nicotinic receptors. The subunit compositions of the gamma-aminobutyric acid- and levamisole-sensitive receptors have been elucidated, but the levamisole-insensitive acetylc...

Recently, both the media and medical literature have directed attention towards neutropenia associated with levamisole-adulterated cocaine. Levamisole, available in South America as an anti-helminthic veterinary agent, was previously used in the United States (US) for treatment of colon cancer and rheumatoid arthritis. Due to its well-established adverse effect of reversible neutropenia in appr...

The United States Public Health Service Administration is alerting medical professionals that a substantial percentage of cocaine imported into the United States is adulterated with levamisole, a veterinary pharmaceutical that can cause blood cell disorders such as severe neutropenia and agranulocytosis. Levamisole was previously approved in combination with fluorouracil for the treatment of co...