نتایج جستجو برای: letal toxin b

تعداد نتایج: 942877  

Journal: :مجله دانشگاه علوم پزشکی شهرکرد 0
علی میری ali miri biology dept., imam hossein university, tehran, iran; 2human genetic research center, baqiyatallah university of medical sciences, tehran, iran;مرکز تحقیقات زیست شناسی، دانشگاه جامع امام حسین(ع)، تهران، ایران جعفر سلیمیان jafar salimian chemical injuries research center, baqiyatallah university of medical sciences, tehran, i.r. iran. tel: 00982182482481,تهران- دانشگاه علوم پزشکی بقیه الله(عج- مرکز تحقیقات آسیب های شیمیایی- تلفن: 82482491-021، احسان رضایی ehsan rezai 1biology dept., imam hossein university, tehran, iran;4chemical injuries research center, baqiyatallah university of medical sciences, tehran, iran;4chemical injuries research center, baqiyatallah university of medical sciences, tehran, iran; 4chemical injuries research center, baqiyatallah university of medical sciences, tehran, iran;1مرکز تحقیقات زیست شناسی، دانشگاه جامع امام حسین(ع)، تهران، ایران4 مرکز تحقیقات بیوتکنولوژی کاربردی، دانشگاه علوم پزشکی بقیه الله (عج)، تهران، ایران غلامرضا اولاد gholamreza olad chemical injuries research center, baqiyatallah university of medical sciences, tehran, iran;مرکز تحقیقات بیوتکنولوژی کاربردی، دانشگاه علوم پزشکی بقیه الله (عج)، تهران، ایران مجتبی سعادتی mojtaba sadati biology dept., imam hossein university, tehran, iranمرکز تحقیقات زیست شناسی، دانشگاه جامع امام حسین(ع)، تهران، ایران محمد علی عارف پور ترابی mohammad ali arefpour-tehrani biology dept., imam hossein university, tehran, iranمرکز تحقیقات زیست شناسی، دانشگاه جامع امام حسین(ع)، تهران، ایران فرید عزیزی جلیلیان

background and aims: among the bacterial agents, the most common cause of diarrheal disease is entrotoxigenic escherichia coli. letal toxin b (ltb) subunit of lt toxin could induce six-month immunity. clostridium botulinum causes botulism disease. bont/a-hc toxin subunit could induce two years immunity against this disease. it seems that the immunogenicity potency of these two subunits may infl...

Journal: :Cancer research 2004
Jose R Conejo-Garcia Fabian Benencia Maria C Courreges Phyllis A Gimotty Eugene Khang Ronald J Buckanovich Kenneth A Frauwirth Lin Zhang Dionyssios Katsaros Craig B Thompson Bruce Levine George Coukos

The role of the NKG2D immunoreceptor and its ligands in antitumor immune response is incompletely understood. Here, we report that effector immune cells infiltrating ovarian carcinoma are mostly CD8+ lymphocytes lacking CD28 but expressing the NKG2D costimulatory receptor. Human ovarian carcinoma expresses the novel NKG2D ligand lymphocyte effector cell toxicity-activating ligand (Letal). Letal...

Ali Ahmadi Jafar Amani Jafar Salimian, Najmeh Poursasan

Background: T-2 mycotoxin belongs to the Trichothecene family and has damaging effects on the immune system. Objective: To investigate the toxic effect of T-2 toxin on the percentage of peripheral blood B lymphocytes and the potential protective role of selenium and vitamin E. Method: Frequencies of B lymphocytes (CD19+ ) were analyzed after injection of sublethal doses of T-2 toxin into Balb/c...

Journal: :iranian journal of immunology 0
ali ahmadi applied microbiology research center, baqiyatallah university of medical sciences najmeh poursasan institute of biochemistry and biophysics, university of tehran jafar amani applied microbiology research center, baqiyatallah university of medical sciences jafar salimian chemical injuries research center, baqiyatallah university of medical sciences, tehran, iran

background: t-2 mycotoxin belongs to the trichothecene family and has damaging effects on the immune system. objective: to investigate the toxic effect of t-2 toxin on the percentage of peripheral blood b lymphocytes and the potential protective role of selenium and vitamin e. method: frequencies of b lymphocytes (cd19+ ) were analyzed after injection of sublethal doses of t-2 toxin into balb/c...

Journal: :iranian red crescent medical journal 0
nima mirzaei department of biology, science and research branch, islamic azad university, tehran, ir iran; department of biology, science and research branch, islamic azad university, tehran, ir iran. tel: +98-2188962343 talat mokhtari azad department of virology, tehran university of medical sciences, tehran, ir iran rakhshandeh nategh department of virology, tehran university of medical sciences, tehran, ir iran hoorieh soleimanjahi department of virology, tarbiat modares university, tehran, ir iran nour amirmozafari department of microbiology, tehran university of medical sciences, tehran, ir iran

background: sequence variations in glycoproteins of influenza virus surface impel us to design new candidate vaccines yearly. ectodomain of influenza m2 protein is a surface and highly conserved protein. m2e in influenza vaccines may eliminate the need for changing vaccine formulation every year. objectives: in this study, a recombinant baculovirus containing m2e and cholera toxin subunit b fus...

GH Behzadian nejhad R.A Ataei

clostridium difficile has been recognized as the major cause of pseudomembranous colitis.this bacterium produces two toxins(an enterotoxin -cytotoxin and a potent cytotoxin called toxin A and toxin B erespectively).these toxins have implicated in pathogenesis of the disease.however,histopathological effects of their molecular mass less than 100KDa have been essayed.in the persent study,we exami...

M Aleboyeh M Azimi rad M.M Aslani M.R Zali o Azizi S.F Mosavi

Background & Aims: Clostridium difficile has been identified as a pathogen in antibiotic associated diarrhea (AAD), pseudomembranous colitis and also nosocomial diarrhea. The present study was performed to find the prevalence of toxigenic strains of C .difficile isolated from diarrhea patients hospitalized in Tehran hospitals. Method: A total of 98 fecal samples obtained during July to December...

Journal: :iranian journal of pharmaceutical sciences 0
hamid madanchi department of biology, imam houssein university, tehran, iran hossein honari department of biology, imam houssein university, tehran, iran mohammad sadraeian department of biology, imam houssein university, tehran, iran mahdi hesaraki department of biology, imam houssein university, tehran, iran

cholera toxin b subunit (ctxb) is a homopantameric, nontoxic subunit of cholera toxin that is responsible for its binding to the cell and has been known as a mucosal adjuvant for vaccines that could increase homoral and mocusal immunity response. in this work, the ctxb gene was fused to the stxb gene from shigella dysenteriae type i a vaccine antigen candidate against this pathogen, by a nonfur...

Clostridium perfringens is a gram-positive, obligate anaerobic bacterium, which is widely distributed in the environment. C. perfringens is subdivided to 5 groups (types A to E), based on its four major toxin (alpha, beta, epsilon and iota). C. perfringens type B beta toxin causes inflammation and bloody necrotic enteritis. Type B related enterotoxaemia is a major problem of veterinary sciences...

Journal: :vaccine research 0
f sadeghpour heravi pertussis reference laboratory‚ department of bactriology, pasteur institute of iran, tehran, iran vs nikbin pertussis reference laboratory‚ department of bactriology, pasteur institute of iran, tehran, iran f shahcheraghi pertussis reference laboratory‚ department of bactriology, pasteur institute of iran, tehran, iran

introduction: despite high level of vaccination against pertussis‚ whooping cough has re-emerged as a health threat, especially in infants. this could be related to expansion of bordetella pertussis with novel alleles for virulence factors including the pertussis toxin promoter, ptxp3. compared to ptxp1 strains‚ ptxp3 strains produce more pertussis toxin which results in immune suppression and ...

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