نتایج جستجو برای: let 7
تعداد نتایج: 709904 فیلتر نتایج به سال:
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Role of KRAS let-7 LCS6 SNP in metastatic colorectal cancer patients We read with interest the study by Zhang et al. [1] on the association between the LCS6 T/G variant (rs61764370) and
Expression of the heterochronic microRNA let-7 is tightly correlated with the onset of adult development in many animals, suggesting that it functions as an evolutionarily conserved developmental timer. This hypothesis has now been confirmed by studies in Drosophila.
سلول های بنیادی مشتق شده از بافت چربی انسانی (hadsc) کاندیدای مورد توجه ای در سلول درمانی بیماری های کبدی اند که تمایل ویژه ای در بدست آوردن خصوصیات کبدی به همراه پتانسیل تکثیر بالاتر و دوره کشت طولانی تر نسبت به دیگر سلول های مزانشیمی حاصل از منابع دیگر دارند. میکروrna ها (mirna ها) دسته ای از rna های غیر کد کننده هستند که به عنوان تنظیم کننده های کلیدی در فعالیت های بیولوژیکی مختلف مانند تکثی...
G3: Genes|Genomes|Genetics has removed 10.1534/g3.114.012203 from early online publication. The early online version of the article was published in error and is instead published early online at GENETICS as 10.1534/genetics.114.169268 at http://www.genetics.org/content/early/2014/07/24/genetics.114.169268, and the version of record will be published in the GENETICS October 2014 issue. The jour...
MicroRNAs (miRNAs) are ubiquitous regulators of eukaryotic gene expression. In addition to repressing translation, miRNAs can down-regulate the concentration of mRNAs that contain elements to which they are imperfectly complementary. Using miR-125b and let-7 as representative miRNAs, we show that in mammalian cells this reduction in message abundance is a consequence of accelerated deadenylatio...
MicroRNAs (miRNAs) are ∼22-nt small RNAs that are important regulators of mRNA turnover and translation. Recent studies have shown the importance of the miRNA pathway in HIV-1 infection, particularly in maintaining latency. Our initial in vitro studies demonstrated that HIV-1-infected HUT78 cells expressed significantly higher IL-10 levels compared with uninfected cultures. IL-10 plays an impor...
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