conclusions our histochemical findings showed a relatively heavy glycosylation of syncytiotrophoblasts of both partial and complete molar tissues, which was prominent in apical portion. this may play a role in their capacity to increase trophoblastic proliferation. results the partial and complete moles generally showed similar reactivity with all used lectins. none of lectins reacted with vill...

Lectins are carbohydrate-binding proteins broadly used in various therapeutic and biomedical applications. The variable affinity of lectins towards variety carbohydrates has raised attention for the biologist to explore functional aspects lectins. express specificity simple example mannose, lactose, sialic acid, complex glycan, glycoproteins. classified based on their sugar as a tool study prot...

objective(s)distinction of hydatidiform moles from non-molar specimens and subclassification of hydatidiform moles as complete and partial are important for clinical practice, but diagnosis based solely on histomorphology suffers from poor interobserver reproducibility. nowadays, pathologists rely on molecular techniques, however these methods are technically difficult, relatively expensive, an...

background: cercariae (larva of helminth parasites) are covered by a thick glycocalyx coat, which serves as an osmotic pro­tection during their free existence, and contain carbohydrates conjugated as glycoproteins, glycolipids and mu­co­polysaccharides. although, limited studies have been made on life cycle of cercariae from fresh water snails, however, car­bo­hydrate studies on cercariae have ...

objective: the development of vertebrae is a complex phenomenon that is correlated with distinct morphological and biochemical alterations in the paraxial mesenchyme and glycoconjugates. the purpose of this study is to investigate the glycosylation pattern in paraxial mesenchyme-forming vertebrae by using the lectin histochemical technique. materials and methods: in this descriptive-analytic st...

Lectins including flowering plant lectins, algal lectins, cyanobacterial lectins, actinomycete lectin, worm lectins, and the nonpeptidic lectin mimics pradimicins and benanomicins, exhibit anti-HIV activity. The anti-HIV plant lectins include Artocarpus heterophyllus (jacalin) lectin, concanavalin A, Galanthus nivalis (snowdrop) agglutinin-related lectins, Musa acuminata (banana) lectin, Myrian...

background: although cockroaches are mechanical vector of many pathogens, still biological transmission of pathogens via these insects is controversial. more covenant immune defense in the hemolymph of cockroaches may take this ad­vantage to block any adaptation of pathogens regarding to biological transmission. lectin molecules in hemolymph of in­sects play as mediators of nonself recognition,...

Influenza virus and other viruses use host cell surface sugars as receptors. Here we show that the sugar-binding domains in influenza virus hemagglutinin and other viral lectins share the same structural fold as human galectins (host lectins). Unlike the easily accessible sugar-binding sites in human galectins, the sugar-binding sites in viral lectins are hidden in cavities. We propose that the...

lectins first discovered more than 100 years ago in plants, they are now known to be present throughout nature. phytohemagglutinin (pha), the lectin extract from the red kidney bean ( phaseolus vulgaris ), contain potent, cell agglutinating and mitogenic activities. they play a role in biological recognition phenomena involving cells and proteins towards medical applications. the present articl...