the effect of a new anthelmintic compound, leavo-tetramisole, in the mass-treatment of several intestinal helminthes has been evaluated during a study undertaken among the population of the village of zavieh hajian, located about 10 km northwest of dezful, khuzestan.in the autumn of 1972, a total of 83 inhabitants, 65 of whom were simultaneously infected with ascaris, hookworm (ancylostoma) and...

Widespread clinical trials of leavo-tetramisole (levamisole) as an immunopotentiating agent in rheumatoid arthritis. metastatic carcinoma, and immunodeficiency states have been complicated by agranulocytosis (AGC) in 2.5%-i 3% of patients. Other than a relationship with prolonged high dosage, very little is known regarding the pathogenesis of levamisole-induced AGC. Whereas leukoagglutination w...

Widespread clinical trials of leavo-tetramisole (levamisole) as an immunopotentiating agent in rheumatoid arthritis, metastatic carcinoma, and immunodeficiency states have been complicated by agranulocytosis (AGC) in 2.5%-13% of patients. Other than a relationship with prolonged high dosage, very little is known regarding the pathogenesis of levamisole-induced AGC. Whereas leukoagglutination wa...

The use of “purified” cooling agents in pharmaceutical and cosmetic preparations only dates back to the late 1880s with the commercial production of menthol from Japanese peppermint (Mentha arvensis) oil in Japan (1). The cultivation of peppermint in Japan before the Christian era appears to predate any other country, and menthol is reputed to have been used medicinally for almost as long (2). ...