langerhans cell histiocytosis (lch) is a rare disorder described as three different entities including eosinophilic granulomaof bone, the hand-schuller-christian syndrome, and letterer-siwe disease. lch is currently classified into singlesystem lch, and multisystem lch. patients with single system lch have an excellent prognosis, and are mostlytreated with local therapy. multisystem lch is subd...

Langerhans cell histiocytosis (LCH) and malignancy occurring in the same individual is unusual and has generally been the subject of isolated case reports. To better define the occurrence of these events a registry of cases with synchronous or asynchronous LCH and malignancy was developed with the cooperation of the Histiocyte Society. In 1991 the Histiocyte Society surveyed its members request...

The developments of lidocaine chloride loaded nanoparticles are encouraging biomaterials, which could be used for wound healing applications abdominal pain management. current work presents the composition dressings based on (LCH) (anesthetic drug)-loaded Polymyxin (PMN)/Glycol (GLY). LCH nanocomposite (LCH@PMN/GLY) were fabricated by oxide solutions within PMN/GLY matrix. influences different ...

Langerhans cell histiocytosis (LCH) is a rare disorder described as three different entities including eosinophilic granulomaof bone, the Hand-Schuller-Christian syndrome, and Letterer-Siwe disease. LCH is currently classified into singlesystem LCH, and multisystem LCH. Patients with single system LCH have an excellent prognosis, and are mostlytreated with local therapy. Multisystem LCH is subd...

Langerhans cell histiocytosis (LCH) involving the thyroid gland is extremely rare. Currently, the diagnosis and therapeutic evaluation for LCH involving thyroid is a challenge.We reported a rare case of LCH involving thyroid, presenting as painless thyroid goiters, and successfully performed positron emission tomography/computed tomography (PET/CT) to make an accurate diagnosis and therapeutic ...

This study aimed to analyze children with the diagnosis of Langerhans cell histiocytosis (LCH) who were diagnosed and treated between 1998-2015. Medical records were evaluated retrospectively for clinical and laboratory features, treatment details, and outcome. There were 20 patients, the median age of diagnosis was 37 months, M/F ratio: 1.5. Nine had single system (SS), 11 had multisystem (MS)...

BACKGROUND Langerhans cell histiocytosis (LCH) is a rare hematopoietic disorder of unknown pathogenesis. LCH diseases may occur in a single organ or multisystem organ. The patients with multisystem involvement usually have a poor prognosis. Liver involvement in multisystem LCH results in severe complications, such as obvious sclerosing cholangitis (SC) with jaundice. METHODS We reported a 31-...

•LCH of the female reproductive tract has four patterns of involvement.•A comprehensive literature review revealed 35 cases of pure genital LCH.•We report two new cases of pure LCH lesions of the vulva and one of the cervix.•Treatment of LCH varies and there is no standard for pure genital involvement.•Prognosis of LCH confined to the gynecologic tract appears to be favorable.

Langerhans cell histiocytosis (LCH) is a malign proliferation of dendritic cells which are able to infiltrate any organ and system. LCH could be restricted to a single organ. In adults, LCH is usually restricted to the lungs. Skin involvement of LCH in adults is rare. However, in pediatric group, skin is a one of the predominant organ which LCH involves solely or as a part of systemic disease. ...

Address correspondence to: Dr. Arunkumar Krishnan, C-137, Karthikeyan salai, Periyar Nagar, Perambur, Chennai-600083, Tamilnadu, India; E-mail: [email protected] Langerhans cell histiocytosis (LCH), previously known as histiocytosis X, encompasses a diverse group of proliferative disorders characterized by infiltration and accumulation of histiocytes and other immune effector cells w...