behcet's disease (bd) is a multisystemic inflammatory disease that occurs most often between the second and fourth decade of life. patients have been reported during the first months of life and after 70 years. our objective was to determine the clinical, paraclinical and genetic characteristics of bd in patients aged < 20 and > 40 years. we conducted a comparative retrospective study including...

background: exposure to endogenous hormones such as estrogen is known as a lifetime breast cancer (bc) risk factor. polymorphisms in genes that are involved in the steroidogenic process, such as cytochrome p450c17alpha ( cyp17) , affect individuals’ susceptibility to bc. in iran, the highest incident of bc is among young women. this study aimed to find prevalence of single nucleotide polymorphi...

background : alzheimer's disease (ad) is one of the most common problems for old peoples. etiology of ad is not clear, but genetic factors play a major role in determining a person's risk to develop ad. twin and family studies con-firm that ad has a genetic basis.ad genetics has been split into two broad categories: early-onset and late-onset. eo-ad cases are inherited in an autosomal dominant ...

psoas abscesses could originate from an adjacent source of infection in the abdominopelvic cavity known as a secondary complication of acute appendicitis. however, it is considered as a very rare event when occurring late after the presentation of appendicitis. whether it is the source or complication of acute appendicitis following appendectomy remains unclear. a 25-year-old man was admitted t...

 Abstract Background: Mustard gas, lethal in high doses, affects multiple organs such as skin, eye and respiratory system. We studied the development of late onset mustardinduced polyneuropathy among chemically wounded Iranian veterans. Methods: In this descriptive study, 100 chemically wounded Iranian veterans with severe eye involvement were examined for any signs and symptoms of polyneuropat...

Introduction: Alexander disease is a heterogenous group of diseases with various manifestations based on age of disease onset. This rare leukodystrophy syndrome with mutations in GFAP Gene could present with developmental delay and seizure in infantile form to ataxia and bulbar palsy in adulthood. However psychiatric symptoms are not well-defined and usually evaluate after disease diagnosis not...

Background: Late onset neutropenia (neutropenia after 3 weeks of life) may be a physiological condition without need to prescribe antibiotics, G-CSF, or IVIG. We aimed to determine the association between sepsis and late onset neutropenia in very low birth weight (<1500 gm) infants.&nbsp; Methods: This study was a cross-sectional prospective study in VLBW infants that were admitted in Mahdieh ...

abstract background: mustard gas, lethal in high doses, affects multiple organs such as skin, eye and respiratory system. we studied the development of late onset mustardinduced polyneuropathy among chemically wounded iranian veterans. methods: in this descriptive study, 100 chemically wounded iranian veterans with severe eye involvement were examined for any signs and symptoms of polyneuropath...

Background Late onset sepsis is a frequent complication of prematurity, associated with increased mortality and morbidity. Probiotics may prevent late onset sepsis in premature infants. The aim of this study was to determine prophylactic effect of oral probiotics in prevention of late onset sepsis of very preterm infants. Materials and Methods This study was a randomized, double blinded, placeb...

Annular pancreas is a relatively rare congenital diseasecaused by an embryologica1and anatomical disturbance in pancreas It may have no sympforns throughout the life and so occasionally discovered during an unrelevant surgery or autopsy but in most of the cases it shows itself as a duodenal obstruction during the in­fancy and childhood.Very rarely symptoms of the disease my be obser­ved in adul...