Although sleep complaints are common in depression and anxiety, there is little agreement as to how they should be organized and assessed. It is also unclear whether sleep complaints show specificity with certain disorders or whether they are nonspecific symptoms. The authors examined the structure of sleep complaints and the relations of these complaints to depression and anxiety in 3 samples:...

A large body of research has demonstrated general relations of sleep complaints with psychological disorders, including anxiety, depression, and dissociation/schizotypy. In contrast, very few studies have focused on the specificity of sleep complaints to daytime symptoms. Identifying sleep disturbances that show evidence of specificity is important for differential diagnosis and assessment. Thi...

Introduction COMP360 is a synthetic, proprietary, purified form of psilocybin in development for treatment-resistant depression (TRD) with FDA Breakthrough Therapy designation. In recent phase IIb study, 25mg was superior to 1mg on change from baseline (CFB) Week 3 the Montgomery-Åsberg Depression Rating Scale (MADRS) total score (primary efficacy endpoint), when administered alongside psycholo...

SUMMARY Thirty two cases are described where the presence of a cluster of neuropsychological symptoms and signs, including unreality feelings, headache, nausea, lassitude, ataxia and tremor, appear to be related to the presence of Air Freshener products. The possible significance of this observation is discussed.

White blood cells, Erythrocyte sedimentation rate and C-reactive protein are sensitive tools to discover rare, but potentially serious pyogenic vertebral osteomyelitis, a disease whose incidence is increasing.