نتایج جستجو برای: lassa fever

تعداد نتایج: 96729  

Journal: :مجله تحقیقات سلامت 0
olayinka ilesanmi department of community health, federal medical centre, owo, ondo state, nigeria bridget omotoso department of community health, federal medical centre, owo, ondo state, nigeria faith alele department of community health, federal medical centre, owo, ondo state, nigeria peter adewuyi nigeria field epidemiology and laboratory training programme, abuja, nigeria

background: lassa fever is an acute, virulent viral haemorrhagic illness with high morbidity and mortality rates. its awareness remain low in sub urban or rural community. this study was carried out to assess the awareness of lassa fever of a rural community in the south western part of nigeria. methodology: a descriptive cross sectional study of 122 respondents prior to a sensitization seminar...

Background: Lassa fever is an acute, virulent viral haemorrhagic illness with high morbidity and mortality rates. Its awareness remain low in sub urban or rural community. This study was carried out to assess the awareness of Lassa fever of a rural community in the south western part of Nigeria. Methodology: A descriptive cross sectional study of 122 respondents prior to a sensitization semina...

Journal: :African health sciences 2014
Nnennaya A Ajayi Kingsley N Ukwaja Ngozi A Ifebunandu Richard Nnabu Francis I Onwe Danny A Asogun

BACKGROUND Lassa fever is a rodent-borne zoonosis that clinically manifests as an acute hemorrhagic fever. It is treated using ribavarin. Surviving Lassa fever without receiving the antiviral drug ribavarin is rare. Only few cases have been documented to date. CASE PRESENTATION We report a case of a 59-year old female with fever who was initially thought to have acute pyelonephritis and sepsi...

2014
Randal J. Schoepp Cynthia A. Rossi Sheik H. Khan Augustine Goba Joseph N. Fair

Sierra Leone in West Africa is in a Lassa fever-hyperendemic region that also includes Guinea and Liberia. Each year, suspected Lassa fever cases result in submission of ≈500-700 samples to the Kenema Government Hospital Lassa Diagnostic Laboratory in eastern Sierra Leone. Generally only 30%-40% of samples tested are positive for Lassa virus (LASV) antigen and/or LASV-specific IgM; thus, 60%-70...

Journal: :The American journal of tropical medicine and hygiene 2007
Phillip Cullison Bonner Wolf-Peter Schmidt Steven R Belmain Babafemi Oshin Debbie Baglole Matthias Borchert

Lassa fever, a viral hemorrhagic fever endemic in parts of West Africa, is a severe febrile illness transmitted to humans by the rodent Mastomys natalensis. To determine risk of Lassa fever in households in Sierra Leonean refugee camps, we analyzed the spatial relationships between households with a Lassa case and focal locations of potential rodent habitats. Quality and hygiene factors of hous...

2012
Danny A. Asogun Donatus I. Adomeh Jacqueline Ehimuan Ikponmwonsa Odia Meike Hass Martin Gabriel Stephan Ölschläger Beate Becker-Ziaja Onikepe Folarin Eric Phelan Philomena E. Ehiane Veritas E. Ifeh Eghosasere A. Uyigue Yemisi T. Oladapo Ekene B. Muoebonam Osagie Osunde Andrew Dongo Peter O. Okokhere Sylvanus A. Okogbenin Mojeed Momoh Sylvester O. Alikah Odigie C. Akhuemokhan Peter Imomeh Maxy A. C. Odike Stephen Gire Kristian Andersen Pardis C. Sabeti Christian T. Happi George O. Akpede Stephan Günther

BACKGROUND Lassa fever is a viral hemorrhagic fever endemic in West Africa. However, none of the hospitals in the endemic areas of Nigeria has the capacity to perform Lassa virus diagnostics. Case identification and management solely relies on non-specific clinical criteria. The Irrua Specialist Teaching Hospital (ISTH) in the central senatorial district of Edo State struggled with this challen...

2015
Nonye Egenti

Introduction: Lassa fever is an acute viral zoonotic illness caused by Lassa virus, an arenavirus known to be responsible for a severe haemorrhagic fever characterized by fever, muscle aches, sore throat, nausea, vomiting, and chest and abdominal pain. The virus exhibits persistent, asymptomatic infection, with profuse urinary virus excretion in Mastomysnatalensis, the ubiquitous and highly com...

2016
Peter O Okokhere Idowu A Bankole Christopher O Iruolagbe Benard E Muoebonam Martha O Okonofua Simeon O Dawodu George O Akpede

The Lassa virus is known to cause disease in different organ systems of the human body, with varying clinical manifestations. The features of severe clinical disease may include bleeding and/or central nervous system manifestations. Whereas Lassa fever encephalopathy and encephalitis are well described in the literature, there is paucity of data on Lassa virus meningitis. We present the clinica...

Journal: :The Journal of infectious diseases 2001
S Günther B Weisner A Roth T Grewing M Asper C Drosten P Emmerich J Petersen M Wilczek H Schmitz

The pathogenesis of neurologic complications of Lassa fever is poorly understood. A Nigerian patient had fever, disorientation, seizures, and blood-brain barrier dysfunction, and Lassa virus was found in cerebrospinal fluid (CSF) but not in serum. The concentration of Lassa virus RNA in CSF corresponded to 1 x 10(3) pfu/mL, as determined by a quantitative real-time polymerase chain reaction ass...

2009
Peter O Okokhere Titus S Ibekwe George O Akpede

INTRODUCTION Lassa fever is an acute arena viral haemorrhagic fever with varied neurological sequelae. Sensorineural hearing loss is one of the rare complications which occur usually during the convalescent stage of the infection. CASE PRESENTATION The cases of two female patients aged 19 and 43 years old, respectively, with clinical features suggestive of Lassa fever and confirmed by immunos...

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