Lanthanum carbonate (LC) is an orally administered phosphate binder. Its absorption is generally thought to be minimal. We report here the case of an 81-year-old woman who underwent subtotal gastrectomy for gastric cancer after receiving hemodialysis for 1 year and taking LC for 7 months. Lanthanum phosphate compounds were found histologically in the gastric mucosa and a regional lymph node and...

Quercetin is the main flavonoid in diet with a potential in the treatment of cancer, cardiovascular, and neurodegenerative diseases. Due to its specific planar chemical structure, quercetin readily forms chelates with metal ions. Complexes of bioactive compounds and metal ions such as lanthanum often show strong cytotoxic and antitumour properties. The aim of this study was to compare the genot...

In order to satisfy the rudder horn casting standards of the International Association of Classification Societies, the properties of ASTM A216 steel should be improved. Therefore, in this article the rudder horn casting and accompanying specimens were cast moulded by arc furnace smelting, external refining, and modification treatment of the molten steel by lanthanum. The samples were first und...

Elevated serum phosphate levels as a consequence of chronic kidney disease (CKD) contribute to the increased cardiovascular risk observed in dialysis patients. Protein restriction and dialysis fail to adequately prevent hyperphosphatemia, and in general treatment with oral phosphate binding agents is necessary in patients with advanced CKD. Phosphate plays a pivotal role in the development of v...

Highly water-soluble lanthanum and cerium citrates or malates with ethylenediaminetetraacetate (NH(4))(8)[Ln(2)(Hcit)(2)(EDTA)(2)]·9H(2)O [Ln = La, 1; Ce, 2], K(8)[La(2)(Hcit)(2)(EDTA)(2)]·16H(2)O (3) and K(6)[Ln(2)(Hmal)(2)(EDTA)(2)]·14H(2)O [Ln = La, 4; Ce, 5] (H(4)cit = citric acid, H(3)mal = malic acid, and H(4)EDTA = ethylenediaminetetracetic acid) were prepared from the reactions of lanth...

Mixed borohydride-chloride complexes of lanthanum and neodymium having the 2,5bis{N-(2,6-diisopropylphenyl)iminomethyl}pyrrolyl ligand in the coordination sphere were synthesised by the reaction of potassium 2,5-bis{N-(2,6-diisopropylphenyl)iminomethyl}pyrrolyl [(DIP2-pyr)K] with a 1:1 mixture of [Ln(BH4)3(THF)3] and LnCl3 (Ln = La, Nd). Both compounds are dimeric in the solid state. The metal ...

In this paper, the applicability of immobilized lanthanum (III) triflate on amine grafted graphene oxide [La(OTf)2-amine grafted-GO] as the first multifunctional catalyst is described for the efficient synthesis of α-aminophosphonates by one-pot three-component reaction of carbonyl compounds, substituted anilines and trialkyl phosphites. Various α-aminophosphonates were synthesized in good to h...

Seven lanthanide diphosphonates, [H3N(CH2)4NH3]Ln[hedpH][hedpH2] (Ln = La, Pr, Sm, Eu, Gd, Tb, Er; hedp = 1–hydroxyethylidenediphosphonate) have been synthesized with 1,4-diaminobutane as the template. The structures were obtained starting from the known X-ray single crystal model of lanthanum compound, with the X-ray powder diffraction data for these seven compounds. H-atoms were introduced us...

BACKGROUND Lanthanum carbonate is a non-calcium phosphate binder that is effective for the treatment of hyperphosphatemia. However, it is unknown whether treatment with lanthanum affects survival. METHODS We retrospectively collected data on maintenance hemodialysis patients at 22 facilities (n = 2292) beginning in December 2008, a time point immediately prior to the commercial availability o...