this study was conducted to determine the properties of islets of langerhans in pancreas of adult and immature, male and female maquee sheep. for this purpose, 20 samples of pancreas were used equally for each male and female, immature and adult animals. paraffin sections that they were stained by h&e; method were used for mean distribution and dimension of langerhans islets, and maldonado stai...

background: langerhans cells are important in the pathogenesis of leprosy.  a recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions.   objective: to investigate a possible relationship between the number of langerhans cells and the histopathologic spectrum of lesions in patients with leprosy.   methods: an immunohistochemical staining for s100 ...

Background: Langerhans cells are important in the pathogenesis of leprosy.  A recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. Objective: To investigate a possible relationship between the number of Langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. Methods: An immunohistochemical staining for S100 prot...

langerhans cell histiocytosis (lch) is the most common type of childhood histiocytic disorder with an incidence of 0.2 to 1 per 100,000 children under the age of 15 years (1). the clinical picture of lch varies from single system (s-s)bone or skin disease to multi-system disease (m-s) (2). we report a neonate with disseminated papulonodular eruption containing mononuclear cd1a and s100 positive...

Langerhans cell sarcoma of the skin is a rare tumor with aggressive behavior. There are reports of Langerhans cell sarcoma involving the skin in patients with underlying systemic Langerhans cell histiocytosis. However, to our knowledge, sarcomatous transformation of skin Langerhans cell histiocytosis, has not been previously described. We report a case of Langerhans cell sarcoma of the skin rep...

Langerhans cell histiocytosis includes a broad spectrum of clinical diseases resulted from proliferation and tissue infiltration of differentiated langerhans cells. This term includes Letterer-siwe disease, Hand-Schuller-Christian disease, eosinophilic granuloma and congenital reticulohistiocytosis that are more common in children than adults. This entity has recently been classified into restr...

conclusions pericardial effusion was a rare finding in this case of langerhans cell histiocytosis. pericardial effusion in langerhans cell histiocytosis, which is an unusual presentation, should be considered when the patient experiences respiratory distress. introduction langerhans cell histiocytosis (lch) is a proliferative disorder of histiocytes in multiple organs. langerhans cell histiocyt...

purpose : fine needle aspiration (fna) cytologic findings of langerhans cell histiocytosis (lch) have been well described, but using this method in the diagnosis of orbital lesions is a recent experience. we hereby report two cases of orbital bone lch diagnosed by fna that later was confirmed by routine h&e; histopathology and immunohistochemistry (ihc) methods. case reports : the first case wa...

Langerhans' cells were studied in the epidermis of two patients with active Behçet's disease and compared with those in two normal controls. Ultrastructural morphology and the percentage of Langerhans' cells found were similar in patients' (1.88%) and the control epidermis (1.79%). The density of Langerhans' cells in adjacent sites of the same epidermis was not homogeneous, being in the range o...