نتایج جستجو برای: lambda protein
تعداد نتایج: 1257257 فیلتر نتایج به سال:
background hepatitis c virus (hcv) is able to down-regulate innate immune response. it is important to know the immune pathways that this virus interacts with. hcv non-structural protein 3 (ns3) plays an important role in this viral feature. hcv ns3 protein could affect the expression of antiviral protein such as viperin, and interleukin 28whichare important proteins in antiviral response. conc...
background: a dinucleotide variant rs368234815 in interferon lambda 4 (ifnl4) gene was recently found to be associated with the hepatitis c virus (hcv) treatment response. this study aimed to assess the impact of ifnl4 rs368234815 polymorphism on treatment response to pegylated?ifn alpha (peg?ifn??) and ribavirin (rbv) in hemophilic patients with chronic hepatitis c (chc). materials and methods...
conclusions there is an as yet unexplained association between hcv and host parameters with unknown mechanisms in patients with chronic hcv infection. the assessments of core aa 70 substitution and polymorphisms near the ifnl3 gene could offer promising steps to improve the management of patients with hcv. background molecular studies have demonstrated that the hepatitis c virus (hcv) genotype ...
Background: Apoptin is a protein from chicken anemia virus that could induce apoptosis specifically in the cancer cells but it has not any effect in the normal cells. Phage therapy is a novel field of cancer therapy and phage nanobioparticles (NBPs) such as λ phage could be modified to deliver and express genetic cassettes into eukaryotic cells safely in contrast with animal viruses. The bacter...
LamB is the cell surface receptor for bacteriophage lambda. LamB missense mutations yielding resistance to lambda group in two classes. Class I mutants block the growth of lambda with the wild-type host range (lambda h+) but support the growth of one-step host range mutants (lambda h). Class II mutants block lambda h but support the growth of two-step host range mutant (lambda hh*) phages. To i...
The immunochemical properties of type 5 M protein antigens that were expressed in Escherichia coli K-12 by recombinant lambda bacteriophages isolated from a gene bank of serotype 5 Streptococcus pyogenes have been analyzed in detail. M proteins from partially purified bacteriophage lysates displayed precipitin lines of identity with a purified peptic extract of type 5 M protein (pep M5) in immu...
We have studied the regulation of the lambda cII gene in vivo using cloned lambda fragments. Lambda N protein stimulated cII expression. Surprisingly, although very high cII protein levels were detected by gel electrophoresis, little cII protein activity, measured as stimulation of the lambda pI and pE promoters, was observed. The half-life of cII protein depended critically on its initial leve...
Lysozyme from lambda bacteriophage (lambda lysozyme) is an 18 kDa globular protein displaying some of the structural features common to all lysozymes; in particular, lambda lysozyme consists of two structural domains connected by a helix, and has its catalytic residues located at the interface between these two domains. An interesting feature of lambda lysozyme, when compared to the well-charac...
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