Beta-lactoglobulins, belonging to the lipocalin family, are a widely studied group of proteins, characterized by the ability to solubilize and transport hydrophobic ligands, especially fatty acids. Despite many reports, the mechanism of ligand binding and the functional role of these proteins is still unclear, and many contradicting concepts are often encountered in the literature. In the prese...

Although the protein nature of antibodies is now firmly established, there is little available information concerning their amino acid composition. Studies recently reported from this laboratory have provided methods of isolation which have made available sufficient amounts of immune proteins for analytical study (l-3). These proteins are for the most part electrophoretically homogeneous, but a...

cow’s milk allergy is one of the most common food allergies in childhood. beta- lactoglobulin (β-  lg) is  a dominant  allergen in  cow’s milk. hydrolysis is  known as  an effective method to reduce the allergenicity of proteins. thus, the objective of this study was to compare the allergenicity of β-lg and its hydrolysates using an animal model. twenty four balb/c mice were divided into three ...

Placental protein 14 (PP14), also known as progestagen-dependent endometrial protein and pregnancy-associated endometrial alpha 2-globulin, is synthesized by the human secretory endometrium and decidua. We have isolated from a human decidual cDNA library clones corresponding to PP14 and deduced its entire amino acid sequence. PP14 contains 180 amino acids, 18 of which correspond to a putative s...

It has already been reported that the principal protein of bovine colostrum is immune lactoglobulin, and a procedure has been described for the isolation of this protein (1). While the immune properties of colostrum have been generally recognized, it is widely believed that this is a specific quality of colostrum, and that immune properties are absent from the later milk or are present only in ...