The initiation of lactation (lactogenesis II) by the mother must be synchronized to the delivery of the infant, permitting the transition of the newborn from continuous nourishment from the umbilical cord to comparable but intermittent life support from its mother's breasts. The onset of lactogenesis II can be adversely affected by a variety of factors. Over 80% of women who have delivered prem...

OBJECTIVE To examine associations between doula care, early breastfeeding outcomes, and breastfeeding duration. DESIGN Prospective cohort. SETTING Regional hospital in northern California. PARTICIPANTS Low-income, full gestation primiparae receiving doula care (n=44) or standard care (n=97). MEASURES Birth outcomes and newborn feeding data obtained from the hospital record. Follow-up in...

Lactogenesis stage II, the onset of copious milk secretion, takes place during the first 4 d postpartum in women and involves a carefully programmed set of changes in milk composition and volume. The evidence is summarized that progesterone withdrawal at parturition provides the trigger for lactogenesis in the presence of high plasma concentrations of prolactin and adequate plasma concentration...

Lactogenesis stage II, the onset of copious milk secretion, takes place during the first 4 d postpartum in women and involves a carefully programmed set of changes in milk composition and volume. The evidence is summarized that progesterone withdrawal at parturition provides the trigger for lactogenesis in the presence of high plasma concentrations of prolactin and adequate plasma concentration...

BACKGROUND Feeding breastmilk to premature infants decreases morbidity but is often limited owing to an insufficient milk supply and delayed attainment of lactogenesis stage II. Early initiation of milk expression following delivery has been shown to increase milk production in mothers of very low-birth-weight (VLBW) infants. Although recommendations for milk expression in this population inclu...

Th e aim of the present study was to evaluate the eff ect of ovine placenta extract, obtained by affi nity chromatography on immobilized wheat germ lectin, on mammogenesis, lactogenesis, and galactopoiesis in pregnant and lactating sheep. Placental extract (100 μg/mL protein concentration) was subcutaneously injected to pregnant sheep in days 1, 4, 7, 10, and 13 of the experiment (totally 10 mL...

Abstract Breastfeeding has long been associated with health benefits for the infant. Breast milk is composed of essential nutrients and bioactive molecules shaping growth, immune development offspring. An optimal mammary gland (MG) during pregnancy critical to maintaining beneficial effects lactation. Nevertheless, how lactation process regulated by system remains largely unexplored. Our data r...