by late 18th or early 19th century, albino rats became the most commonly used experimental animals in numerous biomedical researches, as they have been recognized as the preeminent model mammalian system. but, the precise correlation between age of laboratory rats and human is still a subject of debate. a number of studies have tried to detect these correlations in various ways. but, have not s...

introduction: there is not much data on parasitic infections of laboratory animals that are kept in conventional conditions in iran. the present study was designed to investigate intestinal helminths infections in laboratory colonies of rats and mice. methods: droppings from 110 mice and 110 rats (each animal one dropping) belonging to experimental and breeding groups in four animal houses were...

A major goal of neuroscience is to elucidate mechanisms of cortical information processing and storage. Previous work from our laboratory (Beggs and Plenz, 2003) revealed that propagation of local field potentials (LFPs) in cortical circuits could be described by the same equations that govern avalanches. Whereas modeling studies suggested that these "neuronal avalanches" were optimal for infor...

The practice of animal research is at once familiar and strange. On the one hand, almost everyone knows that it is a regular and widespread part of modern scientific and medical research. Indeed, the idea of being a “lab rat” or “guinea pig” is frequently invoked and readily understood in contemporary discourse. On the other hand, the vast majority of animal research is conducted outside public...