Aims. We previously reported that kamikihito (KKT), a traditional Japanese medicine, improved memory impairment and reversed the degeneration of axons in the 5XFAD mouse model of Alzheimer's disease (AD). However, the mechanism underlying the effects of KKT remained unknown. The aim of the present study was to investigate the mechanism by which KKT reverses the progression of axonal degeneratio...

A comparison beheen a digestion-sedimentation technique IDST) and the Kato-Katz thick smear technique (KKT) in the detection and quantification of Sch,stosoma eggs in stool was carried out in 55 1 sublects Specimen were collected one or two years after treatment with praziquantel from sub ects living in a schistosomiasis endemic area of Mali One hundred infections missed by the KKT were detecte...

We quantify the sensitivity of KKT pairs associated with a parameterized family of nonlinear programming problems. Our approach involves proto-derivatives, which are generalized derivatives appropriate even in cases when the KKT pairs are not unique; we investigate what the theory of such derivatives yields in the special case when the KKT pairs are unique (locally). We demonstrate that the gra...

The Karush-Kuhn-Tucker (KKT) conditions can be regarded as optimality conditions for both variational inequalities and constrained optimization problems. In order to overcome some drawbacks of recently proposed reformulations of KKT systems, we propose to cast KKT systems as a minimization problem with nonnegativity constraints on some of the variables. We prove that, under fairly mild assumpti...

We evaluated the effect of kigikenchuto (KKT), a traditional Japanese formula, in a modified rat pressure-loading skin ulcer model. Rats were divided into three groups, KKT extract orally administered (250 or 500 mg/kg/day for 35 days) and control. KKT shortened the duration until healing. Immunohistochemically, KKT increased CD-31-positive vessels in early phase and increased α-smooth muscle a...

We develop an iterative method for solving the KKT system of the semi-infinite programming (SIP) problem. At each iteration, we solve the KKT system of a nonlinear programming problem with finite constraints by a semismooth Newton method. The algorithm either terminates at a KKT point of the SIP problem in finitely many iterations or generates an infinite sequence of iterates whose any accumula...

We consider Karush-Kuhn-Tucker (KKT) systems, which depend on a parameter. Our contribution concerns with the existence of solution of the directionally perturbed KKT system, approximating the given primaldual base solution. To our knowledge, we give the first explicit result of this kind in the situation where the multiplier associated with the base primal solution may not be unique. The condi...

This paper studies the representation of a positive polynomial f(x) on a noncompact semialgebraic set S = {x ∈ R : g1(x) ≥ 0, · · · , gs(x) ≥ 0} modulo its KKT (Karush-KuhnTucker) ideal. Under the assumption that the minimum value of f(x) on S is attained at some KKT point, we show that f(x) can be represented as sum of squares (SOS) of polynomials modulo the KKT ideal if f(x) > 0 on S; further...

We consider the solution of generalized Nash equilibrium problems by concate-nating the KKT optimality conditions of each player’s optimization problem into a singleKKT-like system. We then propose two approaches for solving this KKT system. The firstapproach is rather simple and uses a merit-function/equation-based technique for the solutionof the KKT system. The second approac...

We consider the solution of generalized Nash equilibrium problems by concate-nating the KKT optimality conditions of each player’s optimization problem into a singleKKT-like system. We then propose two approaches for solving this KKT system. The firstapproach is rather simple and uses a merit-function/equation-based technique for the solutionof the KKT system. The second approac...