background: although cervical cancer mortality has reduced during last years, but it is still leading cause of mortality among women. many efforts have performed to develop new drugs and strategy to cure cervical cancer. mesenchymal stem cells (mscs) have many advantages that make them a suitable choice as a cell therapeutic agent in cancer treatment. there are different transfection methods fo...

background cleft palate (cp) is a common congenital defect. it makes serious difficulties for cleft-affected children. the gold standard of care is autogenous bone grafting which may cause additional problems in donor site along with disappointing results. tissue engineering is a promising solution for a widespread range of defects and disorders. it is reasonable to utilize this novel technolog...

human adipose tissue represents an abundant, practical and appealing source of donor tissue for autologous cell replacement. recent findings have shown that stem cells within the stromalvascular fraction of adipose tissue display a multilineage developmental potential. adipose tissue-derived stem cells can be differentiated towards adipogenic, osteogenic, chondrogenic,myogenic and neurogenic li...

metabolic syndrome is a chronic low-grade inflammation condition which is associated with central obesity, dyslipidemia, insulin resistance and hypertension. inflammation in metabolic syndrome is not only associated with elevated serum inflammatory markers, such as c-reactive protein (crp), but also, is associated with low-grade inflammation in adipose tissue and releasing of adipokines. higher...

background bone marrow and adipose tissue are two main sources of mesenchymal stem cells (mscs). some of studies suggest that there are some differences in gene expression profile of mscs-derived from various tissues. to investigate gene expression profile by qrt-pcr, an appropriate reference gene with stable expression level should be chosen for normalizing data.  this study was designed to ev...

introduction: mesenchymal stem cells can be isolated from adult tissues, such as the adipose tissue, or other sources. among all these sources, adipose tissue because of easy access, and placenta due to its immunomodulatory properties, in addition to another useful properties, were attracted more attention to themselves. isolation and comparing these two different sources can help us for access...

Background Bone marrow and adipose tissue are two main sources of mesenchymal stem cells (MSCs). Some of studies suggest that there are some differences in gene expression profile of MSCs-derived from various tissues. To investigate gene expression profile by qRT-PCR, an appropriate reference gene with stable expression level should be chosen for normalizing data.  This study was designed to e...

objective(s) bone marrow is the traditional source of human multipotent mesenchymal stem cells (mscs), but adipose tissue appears to be an alternative and more readily available source. in this study, rat adipose-derived stem cells (adscs) were induced to differentiate into schwann-like cells and compared with rat bone marrow stem cells (bmscs) for their schwann-like cells differentiation poten...

results the results showed that children with a higher weight z-score spend more time in sedentary activities and less time running or involved in active games. scd-1 activity index, arachidonic/linoleic index, and adipocyte volume were significantly higher in children with a weight z-score greater than 0. the preadipocyte number and the genetic expression of the studied genes did not differ be...