backgrounds: subclinical ketosis can cause greater economic loss due to a lack of clinical symptoms. objectives: the present study was aimed to design a chemical method for measuring serum ketone bodies in the affected subclinical cows. methods: acetoacetate concentrations were measured using a nitroprusside reaction and b-hydroxy butyric acid (bhba) which was oxidized to acetoacetate using nan...

objective(s): the silver nanoparticles, being very small size, can permeate the cellular membrane and interfere in the cell's natural process. in the present study, the effects of time, the dosage of these particles and their use on blood molecules and hormones, the volume of drinking water, and the urine parameters were analyzed.materials and methods: thirty six rats of the wistar race, as sub...

Backgrounds: Subclinical ketosis can cause greater economic loss due to a lack of clinical symptoms. Objectives: The present study was aimed to design a chemical method for measuring serum ketone bodies in the affected subclinical cows. Methods: Acetoacetate concentrations were measured using a nitroprusside reaction and b-hydroxy butyric acid (BHBA) which was oxidized to acetoacetate using nan...

It is now well established that ketone bodies (acetoacetate and D-3-hydroxybutyrate) are metabolized by many mammalian tissues and that the rate of utilization is mainly dependent on their availability in the circulation. The aim in this contribution is to summarize briefly the pathways of ketone-body metabolism and to discuss the role of ketone bodies m various tissues. For a detailed review o...

The effects of ketone bodies on the metabolism of alanine and glutamine were studied in isolated extensor digitorum communis (EDC) muscles from 24 h-fasted chicks. (1) Acetoacetate and DL-beta-hydroxybutyrate (4 mM) markedly inhibit branched-chain amino acid (BCAA) transamination and alanine formation. (2) Ketone bodies (1 and 4 mM) increase the intracellular concentration and release of glutam...

Ketone bodies have been shown to transiently stimulate food intake and modify energy homeostasis regulatory systems following cerebral infusion for a moderate period of time (<6 hours). As ketone bodies are usually enhanced during episodes of fasting, this effect might correspond to a physiological regulation. In contrast, ketone bodies levels remain elevated for prolonged periods during obesit...

A low-carbohydrate ketogenic diet remains one of the most effective (but mysterious) treatments for severe pharmacoresistant epilepsy. We have tested for an acute effect of physiological ketone bodies on neuronal firing rates and excitability, to discover possible therapeutic mechanisms of the ketogenic diet. Physiological concentrations of ketone bodies (beta-hydroxybutyrate or acetoacetate) r...

Elite athletes and coaches are in a constant search for training methods and nutritional strategies to support training and recovery efforts that may ultimately maximize athletes' performance. Recently, there has been a re-emerging interest in the role of ketone bodies in exercise metabolism, with considerable media speculation about ketone body supplements being routinely used by professional ...