PURPOSE To describe the morphologic features of Fuchs corneal dystrophy and compare them with those of bullous keratopathy. METHODS This was an observational case series. The study group consisted of 32 corneal buttons with a diagnosis of Fuchs dystrophy and the comparison group consisted of 22 corneal buttons with bullous keratopathy. Morphologic analysis was performed of corneal buttons fro...

PURPOSE Expression of cellular adhesion molecules is altered in bullous keratopathy. The hypothesis that epithelial alterations in bullous keratopathy compromise the surface of the cornea and its glycocalyx was tested. METHODS Studies were performed on eight cases each of pseudophakic bullous keratopathy and healthy corneas. The number of epithelial cell layers was determined with a stereolog...

A high incidence of band keratopathy was observed in a rabbit colony being utilized in uveitis experiments. Unrelated to the uveitis, the animals had developed, in addition to the corneal lesions, deposits of calcium in the kidneys, arterial tree, trachea, and smooth muscle of the intestine suggestive of hypercalcemia due to an accidental hypervitaminosis D. The clinical and histopathologic cha...

PURPOSE To determine the type and prevalence of epithelial abnormalities in the intermediate postoperative period after penetrating keratoplasty and to define the donor and recipient variables that influence the status of the graft epithelium. DESIGN Prospective cohort study. METHODS We prospectively followed the clinical course of 80 patients after penetrating keratoplasty. We monitored th...

PURPOSE The aim of this study was to investigate transcriptional activities of genes encoding transforming growth factor (TGF)-beta isoforms in bullous keratopathy corneas. METHODS The study group consisted of 45 patients with bullous keratopathy (22 females and 23 males). The control group included 45 corneal donors (21 females and 24 males). Quantification of TGF-beta1, TGF-beta2, and TGF-b...

PURPOSE To report a case of visually significant band keratopathy associated with ocular inflammation and systemic hypercalcemia which markedly decreased in severity after treatment of these underlying factors. METHODS Retrospective case report. RESULTS A 53-year-old Asian female with granulomatous panuveitis in the left eye presented with diffuse band keratopathy through the central cornea...

BACKGROUND Patients with reduced consciousness level suffer from eye protection disorder and Keratopathy. This study was conducted to compare effect of three eye care techniques in prevention of keratopathy in the patients hospitalized in intensive care unit of Kermanshah.   METHODS This clinical trial was conducted in 2013 with sample size of 96 persons in three random groups. Routine care i...

Background & Aims: This study was carried out to determine the leading indications for corneal transplantation in Kerman province. Methods: Medical records of 186 patients underwent corneal transplantation during 3 years (2004-2006) in Shafa Medical Center were evaluated retrospectively. The initial diagnosis and causes of corneal grafting were recorded. Infectious keratitis (Bacterial, Fungal,...