نتایج جستجو برای: jun
تعداد نتایج: 15998 فیلتر نتایج به سال:
background: the mitogen-activated protein kinase (mapk) pathway is one of the major signaling pathways that transmit intracellular signals initiated by extracellular stimuli to the nucleus. the stress-activated protein kinase (sapk)/c-jun nh2-terminal kinase is a subfamily of map kinases implicated in cytokine and stress responses. objective: in this study, we have examined total and phosphoryl...
Background: Resveratrol (RSV) provides several important biological functions in wide variety of cells. In this study, we investigated the molecular mechanisms underlying anti-inflammatory effect of RSV on HepG2 cells by assessing the gene expression of RelA and c-Jun- subunits of NF-κB and AP-1 transcription factors. Methods: HepG2 cells were settled in a serum- free medium...
We compared the ability of cellular and viral Jun (c-Jun and v-Jun) to transactivate target genes. c-Jun and v-Jun bind specifically to 12-O-tetradecanoylphorbol-13-acetate responsive elements [TREs, also called activator protein 1 (AP-1) motifs]. However, whereas c-Jun activates TRE-controlled promoters, v-Jun represses them. Cotransfection of the two Jun proteins reduces c-Jun-dependent trans...
"Volume 2022 (2022): Issue 151 (Jun 2022): Cyprus: Article IV Consultation-Press Release; Staff Report; and Statement by the Executive Director for Cyprus" published on 01 Jun International Monetary Fund.
Ye Won JEON, Woohyung LEE*, Yejong PARK, Bong Jun KWAK, Eunsung JUN, Ki Byung SONG, Dae Wook HWANG, Jae Hoon LEE, Song Cheol KIM. Ann Hepatobiliary Pancreat Surg 2023;27:S62. https://doi.org/10.14701/ahbps.2023S1.OP-1-4
The AP-1 transcription factor c-Jun has been shown to be essential for stress-induced apoptosis in several models. However, the molecular mechanisms underlying the proapoptotic activity of c-Jun are poorly understood. We identify the apoptosis-antagonizing transcription factor (AATF) as a novel nucleolar stress sensor, which is required as a cofactor for c-Jun-mediated apoptosis. Overexpression...
Yejong PARK, Dae Wook HWANG, Jae Hoon LEE, Ki Byung SONG, Eunsung JUN, Woohyung Bong Jun KWAK, Sarang HONG, Song Cheol KIM*. Ann Hepatobiliary Pancreat Surg 2022;26:S360. https://doi.org/10.14701/ahbps.2022S1.EP-80
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