AT the present time jaundiced eyes are frequently rejected as sources of donor material for corneal grafting or for vitreous implantation. One reason for not using these eyes is their discoloration (Edwards and Locke, 1960). This investigation was undertaken in the hope that adequate reasons for or against the use of jaundiced eyes would be discovered. The bilirubin content of the ocular fluids...

In this study, we investigated the affect and the role of growth factors on liver damage. 110 Sprague-Dawley rats were divided into 11 groups: a sham group, a control group, HGF, EGF, IGF, TGF groups of irreversible jaundiced rats and a control group and HGF, EGF, IGF, and TGF groups of reversible jaundiced rats (n = 10). In the irreversible jaundiced groups, the common bile duct was explorated...

Prolyl hydroxylase was estimated in the skin of 24 jaundiced patients and 25 non-jaundiced patients. The activity of this enzyme was markedly reduced in the skin of the jaundiced patients.

The glutathione S-transferases (GSTs) are a family of isoenzymes involved in the detoxication of a variety of electrophilic xenobiotics. The present investigation demonstrates that GST activity and the concentration of cytosolic GSTs in cerebellar cortex of Gunn rats were increased in hyperbilirubinaemic animals compared with non-jaundiced controls. Age-dependent and region-specific increases i...

Exchange transfusion and phototherapy remain the staples of intervention for the jaundiced newborn. Clinical management of the jaundiced low birthweight infant is discussed.

Jaundiced mice, ja/ja, suffer from a severe hemolytic anemia caused by a complete deficiency of erythroid beta-spectrin. We used these mice as a model to investigate the pathophysiological consequences of the deficiency, including the effects in the nonerythroid tissues where this protein is expressed. Because the ja/ja mice rarely survive beyond the fourth postnatal day, methods were assessed ...

on non-jaundiced patients (Clairmont and Von Haberer, 1911; Aird, 1953 ; Zollinger and Williams, 1956). Considerable decreases in renal blood-flow have been shown to occur with traction on viscera during abdominal operations (de Wardener, 1955) or in shock (Lauson et al., 1944). It is possible that obstructive jaundice renders the kidney more sensitive to decreased blood-flow-that is, anoxia. E...

We have examined 26 consecutive jaundiced patients referred to the ultrasound clinic. A differentiation between extrahepatic and other causes of jaundice was possible in 23 of the 24 patients satisfactorily examined. The use of ultrasonic techniques in the jaundiced patient offers a high degree of accuracy to the clinician, and little or no discomfort to the patient.