Creutzfeldt-Jacob disease is the most common form of prion diseases, which have become public health problems in the last two decades because of the high number of reported cases of mad cow disease in Great Britain and other countries. Creutzfeldt-Jacob disease is a fatal situation with known cardinal clinical features including progressive memory loss and myoclonic seizure disorder. In this re...

creutzfeldt-jacob disease is the most common form of prion diseases, which have become public health problems in the last two decades because of the high number of reported cases of mad cow disease in great britain and other countries. creutzfeldt-jacob disease is a fatal situation with known cardinal clinical features including progressive memory loss and myoclonic seizure disorder. in this re...

creutzfeldt-jacob disease is a prion disease which has a wide range of clinical presentations. its diagnosis is not simple and clinical manifestation along with eeg, mr imaging findings and cerebrospinal fluid (csf) analysis should be considered for a definite diagnosis. a-50-year-old woman referred with cognitive impairment, myoclonic jerks, mutism and difficulty in swallowing to our clinic. e...

a biopsy diagnosed patient with creut7,{eldt-jacob diseaseis reportedin. iran. this 53~year-old hunte'r,esented  n may 1994 to mehr hospital with typica clinical manifestations of creunfeldi-jacob disease and died 4 months later. brain biopsy revealed severe neuronal loss, spongiosis and gliosis oj cerebral cortex. e;xposureofthis hunter to the brain tissue ofanimals may explain the route of tr...

Jacob disease is a rare condition consisting of pseudo joint formation between enlarged mandibular coronoid process and the inner surface of the zygoma. We report a 16-years-old male patient with Jacob disease who presented with restricted mouth opening and swelling of the right zygoma. In this report, clinical, radiological, and histopathological findings of the Jacob disease and its surgical ...

1. Mehndiratta MM, Bajaj BK, Gupta M et al : Creutzfeldt-Jacob disease : Report of 10 cases from North India. Neurol India 2001; 49 : 338-341. 2. Shankar SK, Satish Chandra P : Creutzfeldt-Jacob disease – Cases in India in 30 years (1968-1997). CJD Registry NIMHANS, Bangalore, India. 3. Singhal BS, Dastur DK : Creutzfeldt – Jacob Disease in Western India. Observation in 7 patients. Neuroepidemi...

Jacob sheep (Ovis aries) are a pedigree breed known for their "polycerate" (multihorned) phenotype. We describe a four-horned Jacob lamb that exhibited progressive congenital hindlimb ataxia and paresis, and was euthanased four weeks post-partum. Necropsy and CT-scan revealed deformity and asymmetry of the occipital condyles, causing narrowing of the foramen magnum and spinal cord compression. ...