Makale, izoniazid ve N'-(2-(5-((teofilin-7-il)metil)-4-etil-1,2,4-triazol-3-iltio)asetil)izonikotinohidrazit. Deri altı uygulama için hesaplanan N'-(2-(5-((teofilin-7-il)metil)-4-etil-1,2,4-triazol-3-iltiyo)asetil)izonikotinohidrazid dozu, etkili güvenli bir tüberkülosidal ilaç olarak veterinerlik uygulamaları beklentiler.

Sixty-one isolates of M. bovis (58 from cattle and three from wild animals) from eight regions of Poland were analysed. Molecular analysis was done using HAIN and spoligotyping methods. Drug susceptibility of the isolates to streptomycin, izoniazid, rifampicin, ethambutol, and pyrazinamide was tested by proportional methods on solid and liquid media. By spoligotyping, 47 (77%) isolates were ide...

background and objectives: the aim of this study was to investigate the significance of multiple-mutations in the katg gene, predominant nucleotide changes and its correlation with high level of resistance to isoniazid in mycobacterium tuberculosis isolates that were randomly collected from sputa of 42 patients with primary and secondary active pulmonary tuberculosis from different geographic r...

Uprkos činjenici da su lekovi protiv tuberkuloze otkriveni pre više od 50 godina i da je tuberkuloza izlečiva bolest, ona i danas predstavlja veliki zdravstveni i socijalni problem kako u zemljama u razvoju, tako i u visokorazvijenim zemljama. Prema podacima Svetske zdravstvene organizacije (SZO) u svetu se godišnje registruje 8−10 miliona novoobolelih, a svake godine od ove bolesti umire oko d...