conclusions the combination of intravenous paracetamol 1 gr and ketamine 0.5 mg/kg resulted in an overall reduction in pain scores, decreased postoperative analgesic requirements, and lower agitation score compared with intravenous paracetamol 1 gr and tramadol 0.7 mg/kg for patients undergoing renal surgery. results postoperative pain scores were significantly lower in the pk group than in the...

Background Vomiting is a common side effect of ketamine in children's sedation and there is still controversy about the use of an anti-emetic drug along with ketamine to reduce this complication. The aim of this study was to evaluate the effectiveness of ondansetron in controlling vomiting induced by intramuscular (IM), and intravenous (IV) ketamine for procedural sedation and analgesia in chil...

Background Ketamine is an antagonist receptor of N-methyl-D-aspartate (NMDA), and phencyclidine derivate sedative agent. Thus the aim of this study was to evaluate the effect of intravenous (IV) and intramuscular (IM) injection of Ketamine for sedation procedure of children. Materials and Methods In this randomized clinical trial the patients, 1-6 year-old children referred to Emergency Departm...

the aim of this study was to determine the effect of thiopental sodium with that of midazolam-ketamine on relieving agitation after tonsillectomy in children. in a clinical trial, 50 children aged 5-10 years, candidates for tonsillectomy, were randomly divided into two 25-member groups. in the first group, thiopental sodium 5mg/kg/iv, and in the second group combination of midazolam 0.01 mg/kg/...

BACKGROUND Nonconvulsive status epilepticus (NCSE) is a diagnosis that is often challenging and one that may progress to refractory NCSE. Ketamine is a noncompetitive N-methyl-d-aspartate antagonist that increasingly has been used to treat refractory status epilepticus. Current Neurocritical Care Society guidelines recommend intravenous (IV) ketamine infusion as an alternative treatment for ref...

in this study, the aim was the evaluation of effect of intravenous (iv) administration of ketamine, peritonsillar infiltration of tramadol and their combination for control of post-operative pain in comparison with single use of each drug in children undergoing tonsillectomy. one hundred and twenty children, aged 2-15 years, selected for elective adenotonsillectomy were enrolled in the study. w...

BACKGROUND Ketamine has been well studied for its efficacy as an analgesic agent. However, intranasal (IN) administration of ketamine has only recently been studied in the emergency setting. The objective of this study was to elucidate the efficacy and adverse effects of a sub-dissociative dose of IN Ketamine compared to IV and IM morphine. METHODS A single-center, randomized, prospective, pa...

UNLABELLED Laparoscopy is an effective method of implantation for peritoneal dialysis (PD) catheters. Use of the laparoscopic technique is increasing because of its potential advantages over other techniques. In most patients, selection for PD is based on negative criteria, and because of the need for general anesthesia, the laparoscopic technique can be life-threatening in these patients. On t...

Background In recent years, ketamine has been the most used sedative in Emergency Department (ED) procedures for pain management. Therefore, this study evaluated ketamine associated vomiting (KAV) in children requiring sedation. Materials and Methods This is a prospective, randomized, and open trial study carried out on children of ages 3 months to 13 years requiring sedation for medical diagn...

OBJECTIVES Ketamine is commonly used in anesthetic and sedation before surgical procedures and acts as an analgesic in smaller doses. The aim of this study was to assess the effects of intranasal (IN) ketamine in patients with moderate to severe limb trauma (visual analog scale (VAS) > 60 mm). METHODS In a triple-blind randomized controlled clinical trial; 154 patients with isolated orthopedi...