Background: Immune thrombocytopenic purpura (ITP) is a disease characterized by decrease of the peripheral blood platelet count. The disease presents in acute and chronic forms. Because of the importance and high prevalence of ITP, it was decided to study the therapeutic response of patients with ITP. Material and Methods: A cross-sectional study was conducted at Ghaem hospital, Mashhad, Ira...

The ITP tool is an experimental inductive theorem prover for proving properties of Maude equational specifications, i.e., specifications in membership equational logic with an initial algebra semantics. The ITP tool has been written entirely in Maude and is in fact an executable specification of the formal inference system that it implements. 1 Getting started To run the current version of the ...

Background: Previous studies about the relationship between bone marrow megakaryocyte count and the chronicity of ITP has yielded paradoxical results. The aim of the present study was to investigate any relationship between the megakaryocyte count in the bone marrow and the chronicity of ITP. Materials and Methods: This study was performed to compare the primary bone marrow aspiration megakar...

The aim of the present study was to examine and understand changes in platelet functions prior to and after the treatment of primary immune thrombocytopenia (ITP) in children. An automatic hematology analyzer and whole blood flow cytometry were used to detect immature platelet fraction (IPF), IPC and membrane glycoproteins (CD62p, PAC-1 and CD42b) in ITP children (ITP group), children with comp...

Abstract Background Immune thrombocytopenic purpura (ITP) is the most prevalent cause of thrombocytopenia in children. Despite the importance of ITP in children under 2- years old, only a few publications are available in the literature. ITP usually presents itself as   isolated thrombocytopenia and mucocutaneous bleeding. Materials and Methods T...

Background: Idiopathic thrombocytopenic purpura is an autoimmune blood disorder in which platelet destruction is mediated by anti-platelet antibodies. There are two forms of ITP: acute and chronic. The aim of the present study was to evaluate the clinical variables in adult patients with acute ITP in west of Iran. Patients and Methods: Medical records of adult patients with diagnosis of acute ...

Background and Objective: Different studies have investigated the link between helicobacter pylori and extra digestive diseases such as idiopathic thrombocytopenic purpura. However, the relationship between ITP and H pylori is less clear. Most of the studies have focused on H pylori eradication in chronic ITP, so we focused on the effect of H pylori eradication on chronicity of ITP in adult pat...