Vancomycin was first isolated in 1957 from the bacteria Amycolatopsis orientalis jungles of Borneo. Its name is derived word “vanquish.” It a bactericidal tricyclic glycopeptide active against gram-positive aerobic cocci and bacilli through inhibition cell wall synthesis. In addition to being first-line therapy for methicillin-resistant Staphylococcus infections, it used as second-line antimicr...