the major objective of the present study was to characterize the effects of oxidants generated b xanthine (x) plus xanthine oxidase (xo) on isolated rat ileum motility. the effects of three concentrations of x/xo on the basal tone of the rat ileum preparation were studied for 20 minutes. developed tensions were measured in mg/mg tissues and then expressed as percentage of baseline tension. also...

Introduction: Thymol has negative ionotropic effect on heart and has direct effect on calcium release from sarcoplasmic reticulum. Some of the herbal plants just like carum copticum consist of thymol. The postganglionic neurons of the gastrointestinal parasympathetic system are located mainly in the myenteric and submucosal plexuses. Stimulation of these parasympathetic nerves causes general...

introduction: thymol has negative ionotropic effect on heart and has direct effect on calcium release from sarcoplasmic reticulum. some of the herbal plants just like carum copticum consist of thymol. the postganglionic neurons of the gastrointestinal parasympathetic system are located mainly in the myenteric and submucosal plexuses. stimulation of these parasympathetic nerves causes general in...

rosa damascena flower is widely used for gastrointestinal (gi) disorders. however, its pharmacological action on isolated ileum has not been studied. in this research, the effect of extract of flower petals of r. damascena mill. growing in kashan, iran, on ileum motility was investigated. hydroalcoholic extract was prepared by percolation method. a section of rat ileum was suspended in an organ...

dracocephalum kotschyi boiss. is a traditional medicine with antispasmodic activities. the objective of this research was to study antispasmodic activities of hydroalcoholic extract of d. kotschyi on rat isolated uterus contractions for comparison with isolated ileum. hydroalcoholic extract was obtained from aerial part of d. kotschyi using percolation method. a portion of rat ileum or uterus w...

Introduction: Thymol has negative ionotropic effect on heart and has direct effect on calcium release from sarcoplasmic reticulum. Some of the herbal plants just like carum copticum consist of thymol. The postganglionic neurons of the gastrointestinal parasympathetic system are located mainly in the myenteric and submucosal plexuses. Stimulation of these parasympathetic nerves causes general in...

Celery (Apium graveolens L.) is a plant species in the family Apiaceae, which has been used in traditional medicine for the treatment of gastrointestinal diseases. This study investigated the effects of aqueous and ethanol extracts from celery leaves on intestinal contractility. Air-dried and powdered leaves were extracted with distilled water and 96% ethanol, respectively. The activities of th...

The present investigation was aimed at determining the effects of hexane, acetone, methanol and aqueous extracts of Acorus calamus leaves (ACHE, ACAE, ACME and ACAQE) on cholinergic and histaminic system using isolated frog rectus abdominis muscle and guinea pig ileum. A dose dependent potentiation of Ach response (anticholinesterase like effect) was found with ACAE and ACME at 0.25, 0.5, 0.75 ...

background& objectives: zataria multiflora boiss is used in traditional medicine to treat gastrointestinal disorders and menorrhagia. the inhibitory effect of this herb on rat uterus contractions has also been reported. the aim of this study was to investigate the effect of zataria multiflora boiss hydroalcoholic leaf extract (zhle) on isolated rat ileum in presence of some known ileum stimulan...

Morphine inhibits small intestinal transit in mice, although few mu-opioid receptors are present in the ileum. The present study focused on the action of morphine in the isolated mouse ileum to reveal the mechanism by which morphine inhibits mouse small intestinal transit. In the isolated circular muscle, morphine caused tonic contraction. This contraction was potently inhibited by naloxone and...