acute lymphoblastic leukemia (all) is one of the most common cancers among children. although there have been tremendous treatments, none of them have led to a precise cure. the use of herbal medicines which are safe and non-toxic have been demonstrated in this study. curcumin is a polyphenol, hydrophobic product that is derived from turmeric plant. curcumin has anti-toxic, anti-bacterial, anti...

ischemia reperfusion injury is the tissue damage caused when blood supply returns to the tissue after a period of ischemia or lack of oxygen. ischemia reperfusion induces cell death and endemic reaction that is one of the most important clinical problems with acute renal failure and renal transplantation. in this study, the effect of pentoxifylline on rat kidney function and cell injury followi...

Embolic occlusion of the peripheral vessels is common in bacterial endocarditis, especially during the terminal stages, but occlusion of the coronary artery in this disease is unusual at any time. Virchow (1856) described coronary embolism in a case of recent endocarditis. Saphir (1933) surveying earlier reports of coronary embolism from all causes, found 35 cases reported since Virchow's origi...

The time relation between autophagy and myocardium ischemia (MI) has never been documented. Therefore, the present study was conducted to find out the exact timings and specific roles that AMP-activated protein kinase (AMPK)-mTOR signaling pathway plays on autophagy and apoptosis in rats' ischemic heart. 36 male Sprague Dawley (SD) rats were divided randomly into control and MI groups (each = 6...