نتایج جستجو برای: ischemic tolerance

تعداد نتایج: 211039  

ژورنال: پژوهش در پزشکی 2008

Background: Recent studies suggest that normobaric hyperoxia (HO) results in ischemic tolerance to reduce ischemia brain injury. In this research, attempts were made to assess threshold of ischemic tolerance induced by normobaric hyperoxia in rat stroke model. Materials and methods: Rats were divided into two ...

Journal: :iranian journal of basic medical sciences 0
meisam shahhoseini department of physiology, faculty of biological sciences, shahid beheshti university, g.c., tehran, iran mohammad reza bigdeli department of physiology, faculty of biological sciences, shahid beheshti university, g.c., tehran, iran institute for cognitive and brain sciences, shahid beheshti university, g.c., tehran, iran

objective(s):every year, a large number of people lose their lives due to stroke. stroke is the second leading cause of death worldwide. surprisingly, recent studies have shown that preconditioning with hyperoxia (ho) increases tissue tolerance to ischemia, ultimately reducing damages caused by stroke. addressed in this study are beneficial contributions from ho preconditioning into reduced har...

Journal: :Journal of Cerebral Blood Flow & Metabolism 2002

اسماعیلی , روانبخش, جعفری , هدایت, رستگارنیا , نجیبه, شفیع پور , ویدا, قائمیان , علی, محمدپور تهمتن , رضاعلی, نصیری , ابراهیم,

Background and purpose: Prevalence of over weight and obesity is increasing in the world. Those over weight are more susceptible to cardiovascular diseases than other individual's. Studies indicate that body fat distribution has a determining role in the identification of risk factors. Also, the relation between BMI, cardiac ischemic pains and exercise test condition in such patients, is in n...

2017
Masatoshi YUNOKI Takahiro KANDA Kenta SUZUKI Atsuhito UNEDA Koji HIRASHITA Kimihiro YOSHINO

Ischemic tolerance is an endogenous neuroprotective phenomenon induced by sublethal ischemia. Ischemic preconditioning (IPC), the first discovered form of ischemic tolerance, is widely seen in many species and in various organs including the brain and the spinal cord. Ischemic tolerance of the spinal cord is less familiar among neurosurgeons, although it has been reported from the viewpoint of ...

Journal: :the iranian journal of pharmaceutical research 0
mehdi rahnema islamic azad university - zanjan branch parisa seyedemadi kharazmi university mohammad reza bigdeli shahid beheshti university shahrebano oryan kharazmi university hassan rafati shahid beheshti university

the prevention of bbb breakdown and the subsequent vasogenic edema are important parts of the medical management of ischemic stroke. the purpose of this study was to investigate the ischemic tolerance effect of rosmarinus officinalis leaf hydro-alcoholic extract (rhe).five groups of animals were designed: sham (underwent surgery without mcao) and mcao groups, the mcao groups were pretreated ora...

2010
Mohammad Reza Bigdeli Fathemeh Mohagheghi

Article history: Received: 9 Aug 2012 Accepted: 18 Dec 2012 Available online: 22 May 2013 ZJRMS 2014; 16(2): 1-5 Ischemic tolerance can protect the brain against cerebral ischemia and neurodegenerative diseases. However, several studies demonstrate ischemic tolerance by various methods, the exact mechanisms of ischemic tolerance has not been clearly understood. In this study, we first studied b...

Journal: :The Journal of biological chemistry 2006
Robert Meller Jennifer Anastasia Cameron Daniel John Torrey Corrin Erin Clayton Andrea Nicole Ordonez David Clifford Henshall Manabu Minami Clara Kay Schindler Julie Anne Saugstad Roger Pancoast Simon

A previous exposure to a non-harmful ischemic insult (preconditioning) protects the brain against subsequent harmful ischemia (ischemic tolerance). In contrast to delayed gene-mediated ischemic tolerance, little is known about the molecular mechanisms that regulate rapid ischemic tolerance, which occurs within 1 h following preconditioning. Here we have investigated the degradation of the pro-a...

Journal: :Journal of Neuroscience 2015

The prevention of BBB breakdown and the subsequent vasogenic edema are important parts of the medical management of ischemic stroke. The purpose of this study was to investigate the ischemic tolerance effect of Rosmarinus officinalis leaf hydro-alcoholic extract (RHE).Five groups of animals were designed: sham (underwent surgery without MCAO) and MCAO groups, the MCAO groups were pretreated ora...

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