BACKGROUND Once considered as the main public health problem in developed countries, obesity has become a major problem throughout the world and developing countries, like Iran, are joining the global obesity pandemic. We determined the prevalence of overweight, obesity, and hypertension in a large cohort of Iranians and compared age-adjusted rates with the rates in the US. METHODS Golestan C...

OBJECTIVE The aim of the present study was to develop reference data for the Iranian population for anthropometric values and cardiometabolic data in comparison with those in Americans, as representative of a Western population. DESIGN The present cross-sectional survey, conducted as part of the baseline survey of a community-based interventional study (the Isfahan Healthy Heart Programme), u...

STUDY QUESTION Do differences in heritable genetic factors explain some of the difference in age at natural menopause (ANM) among populations? SUMMARY ANSWER One single nucleotide polymorphism (SNP)-ANM association (rs16991615) detected in European women was replicated in Iranian women. WHAT IS KNOWN ALREADY Genetics plays an important role in ANM, and well-powered genome-wide association s...

BACKGROUND Gestational diabetes mellitus (GDM) is common problem during pregnancy. Diagnostic criteria of this problem are based on foreign population. Because of differences in racial, cultural, and nutritional characteristics, we need to determine these criteria are suitable for Iranian population. OBJECTIVE To determine whether different diagnostic criteria of gestational diabetes mellitus...

Summary In order to establish the normative curves for BMD in Iranian individuals, we measured BMDs at the lumbar spine and femoral regions of 760 women and 632 men using dual-energy X-ray absorptiometry. This study provides a baseline normative for Iranian individuals. BMD values of Iranian subjects were generally lower than those of the American population. Introduction In order to establish ...

OBJECTIVE The objective of this study was to determine the prevalence of water pipe smoking and its associated sociodemographic factors among Iranian women of reproductive age in Tehran. SUBJECTS AND METHODS This was a population-based cross-sectional study of 1,359 Iranian women aged 15-49 years. The multistage random cluster technique was used to obtain the sample. Questionnaire-based inter...

Breast cancer is the most common cancer in Iran. In the recent years an upward trend has been observed in the Iranian population. Early detection by molecular approaches may reduce breast cancer morbidity and mortality. We provided consultation to 3,782 women diagnosed with early onset breast cancer during the past 15 years (1999-2014). To establish a data set for BRCA gene alterations of the I...

BACKGROUND Metabolic syndrome (MetS) is a complex clustering cardiovascular risk factors such as abdominal obesity, hypertension, diabetes and dylipedemia. It has been a growing health problem in Iranian adults in recent decade. The objective of this article was to review the prevalence of MetS and the corresponding risk factors among Iranian adults. METHODS We conducted a systematic review t...

BACKGROUND Metabolic syndrome (MetS) is the major risk factor for development of type 2 diabetes and cardiovascular diseases in different populations. The aim of this study was to evaluate the prevalence of MetS among Iranian population. METHODS Thirty-four cross-sectional studies were analyzed with a sample of 83227 people. National and international English electronic databases (PubMed, Goo...