ABSTRACT: Transmissible spongiform encephalopathies are neurodegenerative diseases that affect several mammalian species. Bovine spongiform encephalopathy (BSE) is among the mentioned diseases in cattle caused by abnormally fold prion proteins. Polymorphisms of the prion protein gene (PRNP) have been shown to be major determinations for the susceptibility to transmitted perion diseases in human...

The aim of this study was to investigate effects of DGAT1, OPN and PPARGC1A candidate genes on milk production traits in Iranian Holstein cattle. Several papers have studied single nucleotide polymorphisms (SNPs) and their association with economic traits in dairy cows, but the combined effect of these genes has not been examined in Iranian Holstein cattle population. Blood samples were collect...

BACKGROUND The gullet worm, Gongylonema pulchrum Molin, 1857, is a thread-like spirurid nematode found in a variety of mammals worldwide. Its incidences in Iranian cattle of different breed or age have not been reported. The aims of the present study are to disclose the infection status of G. pulchrum in cattle slaughtered in northern region of Iran. METHODS Full-length esophagi of cattle of ...

This study was designed to determine a reference range of haptoglobin (Hp) in Iranian Holstein cattle of different ages and of both sexes, and to evaluate Hp as marker in some inflammatory diseases in Shiraz, a tropical area in southern Iran. Blood samples were collected from the coccygeal vein of 50 clinically healthy cattle and 36 cows with various inflammatory diseases (acute diffuse traumat...

INTRODUCTION Bovine immunodeficiency virus (BIV) and bovine leukemia virus (BLV) have worldwide distributions, but their prevalences in Iran are unknown. We investigated the presence of infections in Iranian Holstein cattle and determined changes in hematological values for infected animals. METHODOLOGY Nested PCR was used on blood samples from 143 animals Holstein cattle to detect proviral B...

This investigation was conducted to identify polymorphism of the leptin gene in Holstein cows, Mazandarani native cattle and buffaloes by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). The frequencies of A and B alleles were 0.4 and 0. 6 in Holstein cows, 0.56 and 0.44 in Mazandarani native cattle, 0.61 and 0.35 in buffaloes, respectively. The heterozygote genoty...

Bovine spongiform encephalopathy (BSE) is a fatal infectious neurodegenerative disease in cattle, characterized by the accumulation of an abnormal, proteaseresistant prion protein (PrPSc) in the brain. BSE is similar to scrapie in sheep and goats and Creuzfeldt-Jakob disease in humans. Susceptibility in cattle hasbeen shown to be under the influence of two polymorphic locations, which are...

To analyze the resistance against Theileria sergenti infection in Holstein and Japanese Black cattle under field conditions, clinical, hematological and parasitological findings in these breeds of cattle that were grazed in the same pasture were examined during the grazing period. Holstein cattle showed a higher level of parasitemia than Japanese Black. With the progression of parasitemia, pack...

The genetic diversity among Canadienne, Brown Swiss, Holstein, and Jersey cattle was estimated from relationships determined by genotyping 20 distantly related animals in each breed for 15 microsatellites located on separate chromosomes. The Canadienne, Holstein, and Jersey cattle had an average of six alleles per loci compared with five alleles for Brown Swiss. Furthermore, a number of potenti...

Bovine tuberculosis is a major economic problem and a potential public health risk. Improved diagnostics like the gamma interferon (IFN-gamma) test with ESAT6 and/or CFP10 could contribute to the control program. We assessed IFN-gamma responses in zebu (Ethiopian Arsi breed) and Holstein cattle kept indoors or in a pasture to tuberculin purified protein derivative (PPD) and an ESAT6-CFP10 prote...