background: ionizing radiation irradiated from iodine-131 can induce dna damage and cell death. the cellular dna damage is the cause of mutation and cancer. the micronucleus assay in polychromatic erythrocytes was applied to assess the radio-protective effect of turmeric extract on genotoxic potential of iodine therapy. materials and methods: thirty six male albino rats were randomly divided in...

Background: Ionizing radiation irradiated from iodine-131 can induce DNA damage and cell death. The cellular DNA damage is the cause of mutation and cancer. The micronucleus assay in polychromatic erythrocytes was applied to assess the radio-protective effect of Turmeric extract on genotoxic potential of iodine therapy. Materials and Methods: Thirty six male albino rats were randomly divided in...

introduction: there is a limited number of case reports published in the past decade confirming the radio-iodine presence in the tear. these observations as well as reported cases of salivary and lacrimal gland dysfunction after radioiodine therapy stimulated investigators to clarify whether lacrimal gland function can be affected post-radioiodine therapy. hence we planned a historical cohort s...

radioactive iodine therapy is commonly used as an adjuvant therapy in follicular and papillary thyroid carcinoma and also in the treatment of graves’ disease. the basis of which is the accumulation of radioactive iodine by the sodium-iodide symporter (nis) in the thyroid gland. expression of nis by extrathyroidal tissues including islets of pancreas has been reported. radioactive iodine uptake ...

introduction: patients administered with a therapeutic dose of 131i for thyroid cancer treatment are potential sources of unacceptably high radiation exposure to other individuals, particularly the patient's immediate family members. the aim of this study is to investigate effects of early liothyronine consumption after radio-iodine therapy on accumulated dose and exposure rate in patients with...

introduction: recombinant human thyroid-stimulating hormone(rhtsh) increases radioactive iodine uptake(raiu) in selected populations, while lithium is used as an adjunct to radioactive iodine (rai) therapy in graves’ disease with low raiu. in this report, both drugs used in combination, overcame low iodine-131 uptake in a graves’ patient. clinical case: a 39-year old female with graves’ disease...

SUMMARY In order to evaluate the long-ter m effects of antithyroids and ahlative therapy on patients with toxic diffuse goiter (TDG) in an iodine deficient region, 206 patients were studied in Tehran. Hyperthyroidism recurred in 50%, of 80 patients treated with Methimazole (MMI), from one week to 48 months after cessation of therapy. Another 40 patients remained in remission. Of 102 patients t...

Background: Ionizing radia on irradiated from iodine-131 can induce DNA damage and cell death. The cellular DNA damage is the cause of muta on and cancer. The micronucleus assay in polychroma c erythrocytes was applied to assess the radio-protec ve effect of Turmeric extract on genotoxic poten al of iodine therapy. Materials and Methods: Thirty six male albino rats were randomly divided in six ...

Radioactive iodine therapy is commonly used as an adjuvant therapy in follicular and papillary thyroid carcinoma (PTC) and in the treatment of Graves' disease (GD). The basis of this therapy is the accumulation of radioactive iodine by the sodium-iodide symporter (NIS) in the thyroid gland. Expression of NIS by extrathyroidal tissues such as islets of pancreas has been reported. Radioactive iod...

in research institute for nuclear medicine (tehran university of medical sciences) 50 patients with follicular thyroid carcinoma were evaluted retrospectively. the purpose of the study was assesment of the response of iodine-131 therapy. the best result were achieved when the patient treated with iodine-131 for the first time, in the 4th decade of life, with total thyroidectomy and no metastasi...