background: it is intriguing and imperative that the comparison of the iron preparations in hemodialysis (hd) patients. th is study aimed to observe the short-term effi cacy of parenteral iron sucrose and ferric chloride in hd patients. materials and methods: this was a consecutive 10-week single-blind study in taiwan. an intravenous iron supplement of 100 mg/week was administered as an infusio...

background functional iron deficiency (fid) may cause erythropoietin resistance in patients under hemodialysis (hd). since the role of chronic inflammation or oxidative stress in its pathogenesis is unclear, controversy remains to whether intravenous iron or intravenous ascorbic acid (an antioxidant) can improve this anemia due to decreased iron availability. objectives the current study compar...

the effect of intravenous and oral iron administration on responsiveness to synthetic erythropoietin in treatment of hemodialysis patients' anemia     shariati ar [1] , asayesh h [2] , mojerloo m [3] , karimi taleghani h [4]     received: 10june, 2011 accepted: august 28, 2011     abstract   background & aims : inadequate production of erythropoietin is the main cause of anemia in chronic ...

A growing body of literature supports the use of intravenous iron as a compliment to erythropoiesis stimulatory therapy and in a significant number of disease states where iron is necessary and oral iron is ineffective or not tolerated. The differences in efficacy, safety, and clinical nature of serious adverse events that occur with the various iron preparations are poorly understood. Misinter...

Intravenous iron supplementation is an effective therapy in iron deficiency anemia (IDA), but controversial in anemia of inflammation (AI). Unbound iron can be used by bacteria and viruses for their replication and enhance the inflammatory response. Nowadays available high molecular weight iron complexes for intravenous iron substitution, such as ferric carboxymaltose, might be useful in AI, as...

Oral iron supplementation is usually the first choice for the treatment of iron deficiency anemia (IDA) because of its effectiveness and low cost. But unfortunately in many iron deficient conditions, oral iron is a less than the ideal treatment mainly because of adverse events related to the gastrointestinal tract as well as the long course required to treat anemia and replenish body iron store...

Intravenous iron is widely used to maintain adequate iron stores and prevent iron deficiency anemia in patients with chronic kidney disease, yet concerns remain about its long-term safety with respect to oxidative stress, kidney injury, and accelerated atherosclerosis, which are the subjects of this review. Three parenteral iron formulations are available for use in the United States: Iron dext...

BACKGROUND AND OBJECTIVES Among patients with chronic kidney disease (CKD), differences in proteinuria are seen between intravenous iron preparations after a single dose exposure. This study examined differences in proteinuria between two intravenous iron preparations after multiple doses. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Patients with iron-deficiency anemia and CKD, stratified b...

BACKGROUND Iron deficiency is the most common disorder in the world, affecting approximately 25% of the world`s population and the most common cause of anemia. OBJECTIVE To evaluate the efficacy and safety of intravenous iron sucrose (IS) in the treatment of adults with iron deficiency anemia METHODS Eighty-six adult patients with iron deficiency anemia, who had intolerance or showed no eff...

OBJECTIVES To compare oral versus intravenous iron in pre-dialysis patients of chronic renal failure (CRF) receiving recombinant human erythropoietin (rHuEPO). METHODS The study was undertaken in 40 adult patients of chronic renal failure. The patients were randomly divided into two groups A and B of 20 patients each. Group A patients were given oral iron and group B patients were given intra...