abstract background: postoperative pain is an important surgical problem. recent studies in pain pathophysiology have led to the hypothesis that with perioperative administration of analgesics (pre-emptive analgesia) it may be possible to prevent or reduce postoperative pain. this study was planned to investigate the efficacy of pre-emptive analgesia on postoperative pain after major gynecologi...

background pain following laparoscopy could be due to different causes requiring effective postoperative analgesia. objectives in the present study, we evaluated the combined effect of intraperitoneal infiltration of bupivacaine-meperidine versus intravenous infusion of paracetamol on pain relief after diagnostic gynecologic laparoscopy. conclusions intraperitoneal infiltration of bupivacaine w...

OBJECTIVE The aim of this study was to compare the postoperative analgesic efficacy of preincisional and intraperitoneal levobupivacaine or normal saline in patients undergoing laparoscopic cholecystectomy. METHODS Sixty patients who participated in the study were randomly divided into 3 groups. Group 1 received intraperitoneal levobupivacaine (0.25% 40 mL) immediately after the pneumoperiton...

Cecal ligation and puncture (CLP) caused septic peritonitis in wild-type (WT) mice, with approximately 33% mortality within 7 days after the procedure. Concomitantly, the protein level of intraperitoneal CX3CL1/fractalkine was increased, with infiltration by CX3CR1-expressing macrophages into the peritoneum. CLP induced 75% mortality in CX3CR1-deficient (CX3CR1(-/-)) mice, which, however, exhib...

Objectives: The aim of this study was to assess the analgesic efficacy of Bupivacaine application at port-site and intraperitoneal infiltration in patients with laparoscopic cholecystectomy. Study Design: Randomized Controlled Clinical Trial. Place and Duration: The study was conducted at Rehman Medical Institute (RMI) Peshawar, Pakistan from June 2009 to June 2012. Materials and Methods: Patie...

BACKGROUND Pain following laparoscopy could be due to different causes requiring effective postoperative analgesia. OBJECTIVES In the present study, we evaluated the combined effect of intraperitoneal infiltration of bupivacaine-meperidine versus intravenous infusion of paracetamol on pain relief after diagnostic gynecologic laparoscopy. PATIENTS AND METHODS In this prospective study, 90 fe...

Fatty change of the liver is an extremely common lesion, generally found as a diffuse process involving the entire organ. Focal fatty infiltration appears to be rather rare and can be found in many different patterns [1]. Delivery of insulin in the peritoneal dialysate, instead of the usual subcutaneous route, is a wellestablished method for diabetic patients on continuous ambulatory peritoneal...