results there was a real faster response in the first group; while groups 3 and 4 had the slowest responses to treatment. rates of responsiveness seemed to have no significant difference between the groups, but side effects were significantly much frequent in the first group. conclusions intralesional triamcinolone acetonide with cryotherapy showed the most efficacies with more adverse effects,...

the current treatment of choice for cutaneous leishmaniasis is either parenteral or intralesional antimonial compounds. each of these treatments has its own downfalls which include toxic side effects with the parentral injection and pain at the site of injection with the intralesional injection. in recent years, there has been more focus on paromomycin as an alternative drug; however, current d...

BACKGROUND Keratoacanthomas (KAs) are a variant of squamous cell carcinomas. Some KAs have shown aggressive behaviour, leading to metastasis and death. Surgical excision is the treatment of choice for most KA patients. Intralesional methotrexate (MTX) may also be a potential treatment option for KAs. OBJECTIVE To evaluate intralesional MTX as a treatment modality for KA. METHODS A retrospec...

background cutaneous leishmaniasis is an endemic disease in iran. although there are several treatment modalities for this disease, pentavalent antimonials are still considered as first line agents. there have been several reports concerning the effectiveness of cassia fistula plant for leishmaniasis treatment. objectives this study was designed to assess the effectiveness of concentrated boile...

background warts are benign tumors of the skin and mucosa and are caused by human papilloma virus (hpv). they are one of the most common skin diseases found mainly in children and adolescents. although most of the warts disappear spontaneously or respond to the usual therapeutic measures, resistant forms of the warts impose a problem in dermatology. intralesional injection of bleomycin has been...

OBJECTIVE To compare the clinical response of keloidal and hypertrophic scars after treatment with intralesional corticosteroid alone or combined with 5-fluorouracil (5-FU), 5-FU alone, and the 585-nm flashlamp-pumped pulsed-dye laser (PDL). DESIGN Prospective, paired-comparison, randomized controlled trial. SETTING A private ambulatory laser facility. PATIENTS Ten patients with previousl...

Periorbital hemangioma may lead to the vision impairment so effective treatment should be adopted in time. In this study, we made a retrospective analysis of intralesional glucocorticoids and systemic propranolol in the management of periorbital hemangioma. From Jan. 2006 to Dec. 2013, twenty-five children with periorbital hemangioma were enrolled into this study. Among them, sixteen children a...

BACKGROUND Because intralesional injection of triamcinolone acetonide (TA), a widely used for the treatment of keloid, is painful, many patients discontinue treatment. We evaluated the effects of pretreatment with topical 60% lidocaine tape on the pain and tolerability of intralesional TA treatment in patients with keloid. METHODS The subjects were 42 patients with keloid who had been treated...

BACKGROUND The aesthetic implications of ear keloids, which affect people of all races, are serious and the treatment of earlobe keloids is known to be difficult. The high rate of recurrence following excision alone has led to investigating various types of adjuvant therapy, including intralesional corticosteroid injection. OBJECTIVE We evaluated the efficacy of excision combined with periope...