introduction: glycoconjugates are a class of glycoproteins or glycolipids, their terminal sugars are responsible for cell-cell and/or cell-extracellular matrix interactions. aberrant glycosylation of these compounds are one of the most important aspects of cellular transformation, metastasis and escape of tumoral cells from immune system and resistance to antineoplastic drugs. recent studies sh...

Biliary (hepatic and extrahepatic) intraductal papillary mucinous neoplasms and intraductal oncocytic papillary neoplasms/carcinoma are rare neoplasms. Classification of biliary intraductal papillary tumors can be confusing and reports in radiology literature are extremely limited. We describe the first reported case of biliary intraductal oncocytic papillary neoplasms/carcinoma in the liver in...

A case of revealing a rare pathology for the mammary glands in men - intraductal papilloma is presented. There features clinical course, mammography and ultrasound visualization results histology. The final diagnosis «intraductal papilloma» established only on basis pathomorphological immunohistochemical studies obtained during excisional biopsy.

CONTEXT An intraductal oncocytic papillary neoplasm is a rare pancreatic tumor with the potential of developing invasive carcinoma. Its differentiation from other cystic-like neoplasms of the pancreas, such as intraductal papillary mucinous neoplasms, is a challenge for pancreatic imaging. CASE REPORT We present the case of a 76-year-old male with painless jaundice caused by an intraductal on...

A 69-year-old woman was referred to our hospital after incidental identification of a pancreatic mass during follow-up for diabetes mellitus. Various imaging examinations showed a tumor in the main pancreatic duct, without apparent hypersecretion of mucin. Brush cytologic examination revealed class V disease (adenocarcinoma). Because preoperative examination suggested an intraductal neoplasm wi...

The management of breast intraductal papillary neoplasms of the breast poses a challenge for clinicians. Intraductal papillary carcinoma and papilloma resemble in their clinical features. The aim of this study was to determine whether a combination of clinical factors could be used to accurately identify intraductal papillary carcinoma. 644 patients diagnosed by breast intraductal papillary neo...

BACKGROUND Intraductal tubular adenoma of the pancreas, pyloric gland type (ITA), is an infrequent intraductal benign lesion located in the main duct and large branch duct of the pancreas. The purpose of this report is to introduce seven new cases and to compare their clinicopathologic features and KRAS mutations to gastric-type intraductal papillary mucinous neoplasms (IPMNs) and intraductal t...

The intraductal approach is particularly appealing in the setting of ductal carcinoma in situ (DCIS), a preinvasive breast neoplasm that is thought to be entirely intraductal in its extent. Based on an emerging understanding of the anatomy of the ductal system as well as novel techniques to leverage the access accorded by the intraductal approach, researchers are actively exploring how ductal l...

Detection of breast cancer at an early stage is the most effective approach to decrease mortality, and bloody nipple discharge is an important clue to detect ductal cancer. In case of bloody nipple discharge the intraductal approach is a minimally invasive method to detect intraductal lesions. The intraductal approach does not destroy the ductal structure and does not cause needle tract dissemi...